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Ryaltris vs. Azelastine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Ryaltris

(olopatadine / mometasone)

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azelastine nasal spray

 

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Summary for Ryaltris

Prescription only

Ryaltris is a combination of two medications: olopatadine (an antihistamine) and mometasone (a corticosteroid). It's a nasal spray used to treat eye and nasal symptoms of seasonal allergies (e.g., runny nose, stuffy nose, sneezing, itchy eyes) in people ages 12 and older. The dosage is 2 sprays in each nostril twice per day. Ryaltris (olopatadine / mometasone) doesn't have a generic version since it's only available as a brand-name medication. Side effects aren't common, but include a bad taste in the mouth and nosebleeds.

Indications for Ryaltris

  • Eye and nasal symptoms of seasonal allergies (e.g., runny nose, stuffy nose, sneezing, itchy eyes)

Pros and Cons for Ryaltris

Pros

  • Combines two first-choice medications into a single spray
  • Starts to work within 15 minutes
  • Less side effects than antihistamines and steroids taken by mouth

Cons

  • Can cause nosebleeds and nasal irritation
  • Need to use twice per day
  • Available by prescription only

Common Side Effects for Ryaltris

Warnings for Ryaltris

  • Nasal problems
  • Drowsiness
  • Eye and vision problems
  • Allergic reactions
  • Risk of infection
  • Altered stress hormone levels
  • Slowed growth in children

Summary for Azelastine

Prescription only

Azelastine nasal spray is an antihistamine that treats allergies and nasal symptoms, such as runny or stuffy nose. The 0.1% and 0.15% strengths of the azelastine nasal spray are available with a prescription for adults and children. It's sprayed into the nostrils typically twice a day. Prescription azelastine nasal spray is a lower-cost generic. Possible side effects include a bitter taste in the mouth and nasal discomfort.

Note: Azelastine 0.15% nasal spray is also available over the counter under the brand name Astepro Allergy.

Indications for Azelastine

  • Seasonal allergy symptoms related to the nose
  • Year-round allergy symptoms related to the nose - azelastine 0.15% spray only
  • Runny or stuffy nose that isn't caused by allergies - azelastine 0.1% spray only

Pros and Cons for Azelastine

Pros

  • Works well to relieve nasal symptoms during allergy season
  • Might work faster than steroid nasal sprays and some oral antihistamines
  • Sprayed directly into the nose
  • Available in two different strengths (0.1% and 0.15%)

Cons

  • Doesn't have a counter to keep track of the number of sprays you have left in the bottle
  • Can leave a bitter taste in your mouth (but it goes away)
  • Can cause sleepiness in some people
  • Might need to use twice a day

Common Side Effects for Azelastine

Azelastine 0.1% nasal spray:

  • Bitter taste in the mouth (20%)
  • Headache (15%)
  • Sleepiness (12%)
  • Nasal burning (4%)

Azelastine 0.15% nasal spray:

  • Bitter taste in the mouth (4%)
  • Nasal discomfort (4%)

Warnings for Azelastine

  • Possible sleepiness and difficulty concentrating

Prices with our coupons for Ryaltris vs. Azelastine

Price Card Drug Icon
Ryaltris1 nasal spray / 240 metered sprays of 665mcg/25mcg/spray
$253.72$304.07
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Azelastine1 nasal spray / 30ml of 137mcg/spray
$19.97$33.19
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