Key takeaways
Ryaltris (olopatadine / mometasone) and Dymista (azelastine / fluticasone) are both combination nasal sprays used to treat allergy symptoms like a runny or stuffy nose. They both contain an antihistamine and a corticosteroid, but they differ in their specific ingredients and some other aspects. Ryaltris combines olopatadine, an antihistamine, with mometasone, a corticosteroid, and is used for people aged 12 and older. Dymista, on the other hand, combines azelastine, an antihistamine, with fluticasone, a corticosteroid, and is approved for use in children as young as 6 years old. Ryaltris is only available as a brand-name medication, while Dymista has a lower-cost generic option. Both medications are taken as nasal sprays, but Ryaltris requires two sprays in each nostril twice a day, whereas Dymista requires one spray in each nostril twice a day. Common side effects for both include a bad taste in the mouth and nosebleeds, and Dymista may also cause headaches. Both medications can cause drowsiness, so you should avoid alcohol and be cautious when driving or operating machinery.
