
Ryaltris
Ryaltris is a nasal spray used to treat symptoms of seasonal allergies like runny or stuffy nose, sneezing, and itchy eyes. It contains two active ingredients: olopatadine (an antihistamine) and mometasone (a corticosteroid). This nasal spray is for adults and children ages 12 and older. You use 2 sprays in each nostril twice a day. Side effects aren't common but can include a bad taste in the mouth and nosebleeds.
What is Ryaltris (olopatadine / mometasone)?
What is Ryaltris (olopatadine / mometasone) used for?
- Symptoms of seasonal allergies in people ages 12 years and older
How Ryaltris (olopatadine / mometasone) works
Ryaltris is a combination of two medications that work together to treat allergy symptoms.
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Olopatadine is an antihistamine. It blocks histamine, a chemical in the body that causes allergy symptoms. This helps relieve runny nose, stuffy nose, sneezing, and itchy eyes.
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Mometasone is a corticosteroid. It helps reduce swelling and irritation in the nose caused by allergies. This also helps treat allergy symptoms.
Drug facts
| Common Brands | Ryaltris |
|---|---|
| Drug Class | Antihistamine / Corticosteroid |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
More on Ryaltris (olopatadine / mometasone) essentials
Side effects of Ryaltris (olopatadine / mometasone)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Change in taste in the mouth (3%)
- Nosebleed (1%)
- Nasal discomfort (1%)
Less Common Side Effects
- Drowsiness
Ryaltris (olopatadine / mometasone) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: hives; rash; swelling in the face, lips, tongue, or throat; trouble breathing
The following Ryaltris (olopatadine / mometasone) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Crusting or sores inside the nose
- Frequent or severe nosebleeds
- Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
- Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
- Thrush—white patches in the nose or mouth
- Whistling through one or both nostrils that does not go away
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Change in sense of smell
- Change in taste
- Drowsiness
- Irritation inside the nose or throat
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Pros and cons of Ryaltris (olopatadine / mometasone)
Pros
- Has two first-choice medications for allergies in a single nasal spray
- Starts to work within 15 minutes
- Few side effects
Cons
- Need to use twice a day
- Can cause nosebleeds and nasal irritation
- Available by prescription only
Pharmacist tips for Ryaltris (olopatadine / mometasone)
- It's not common, but Ryaltris (olopatadine / mometasone) can sometimes cause nosebleeds. To stop a nosebleed, sit upright and lean forward. Pinch the soft part of your nose above your nostrils for about 10 minutes while you breathe through your mouth. Get medical help if the nosebleed is hard to stop or if you feel dizzy.
- Ryaltris (olopatadine / mometasone) can make some people feel sleepy. Don't drive or use heavy machinery until you know how this medication affects you.
- Avoid alcohol and other medications that can make you sleepy while using Ryaltris (olopatadine / mometasone). This can make drowsiness worse.
- Ask your prescriber if it's safe to use Ryaltris (olopatadine / mometasone) with your other medications. Even though you spray it into your nose, it can still interact with some medications you take by mouth. This can include certain antibiotics, antifungals, and antivirals like ritonavir. They can raise the amount of Ryaltris (olopatadine / mometasone) absorbed, which can raise your risk of side effects.
- If you're pregnant or planning to become pregnant: Tell your prescriber. There isn't enough information to know if Ryaltris (olopatadine / mometasone) is safe to use during pregnancy. But both ingredients in the nasal spray are thought to be safe. Your prescriber can help you choose a safe option for your allergies.
- If you plan to breastfeed: Talk to your prescriber about the risks and benefits of using Ryaltris (olopatadine / mometasone) while breastfeeding. It's not known if the medication passes into breast milk or if it affects a breastfed baby. Ask your prescriber or a lactation expert about safe feeding options.
How to use Ryaltris (olopatadine / mometasone) nasal spray:
- Priming Ryaltris (olopatadine / mometasone): Prime each new bottle before using. Shake it well and spray it 6 times into the air away from your face or until you see a fine mist. If you haven't used the nasal spray for 2 weeks or more, prime the bottle again by spraying it twice into the air or until you see a fine mist.
- Before using Ryaltris (olopatadine / mometasone): Blow your nose to clear your nostrils. This makes sure there's nothing blocking the medication when it’s sprayed into your nose.
- How to use Ryaltris (olopatadine / mometasone): Shake the bottle well before each use. Close one nostril with your finger. Then, place the spray tip into the other nostril, aiming it slightly toward your ear. Lean your head forward and spray while gently breathing in through your nose. Then, breathe out through your mouth. Don't spray into your eyes, mouth, or on your nasal septum (the wall between your nostrils).
- After using Ryaltris (olopatadine / mometasone): Avoid blowing your nose for at least 15 minutes so the medication stays in your nose. Also, avoid tilting your head back right away since it can cause the medication to drip into your throat.
- How to clean Ryaltris (olopatadine / mometasone): Wipe the spray nozzle with a clean, dry tissue or cloth after each use.
- What to do if the Ryaltris (olopatadine / mometasone) spray pump gets clogged: Remove the spray nozzle tip and dust cap. Soak the spray tip in warm water for 15 minutes. Then, rinse both the spray tip and dust cap with warm water. Let them dry completely before putting the bottle back together. After cleaning, spray twice into the air to re-prime the bottle before using it again. Don’t use a pin or sharp object to unblock it.
Risks and warnings for Ryaltris (olopatadine / mometasone)
Ryaltris (olopatadine / mometasone) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Nose problems
- Risk factors: Nasal surgery | Injury to the nose | Ulcers in the nose | Using Ryaltris (olopatadine / mometasone) for several months
Using Ryaltris (olopatadine / mometasone) can sometimes cause nose problems. This can include nosebleeds, sores, or damage inside the nose. Sometimes, this damage can affect the tissue between your nostrils (the nasal septum). Tell your prescriber if you have nosebleeds often, crusting inside your nose, or a whistling sound when you breathe.
Ryaltris (olopatadine / mometasone) can also slow healing after a nose injury or surgery. Avoid using the medication if you have a sore in your nose, a nose injury, or recent nasal surgery until it's healed.
Ryaltris (olopatadine / mometasone) can also raise the risk of a fungal infection in the nose or throat (thrush). This might be more likely with long-term use, like several months. Tell your prescriber if you have white patches in the back of your throat or trouble swallowing. Also let them know if you have long-lasting stuffy nose, facial pain or pressure, or thick nasal discharge. These can be signs of thrush.
Drowsiness
- Risk factors: Drinking alcohol | Taking other medications that cause drowsiness
Ryaltris (olopatadine / mometasone) can make you feel drowsy. It can also make it harder to think, react, or focus.
Don't drive, use dangerous machines, or do other activities that need your full attention until you know how Ryaltris (olopatadine / mometasone) affects you. Avoid alcohol and other medications that can cause drowsiness. They can make these side effects worse.
Eye and vision problems
- Risk factors: History of glaucoma or cataracts | History of high pressure in the eye
It's not common, but Ryaltris (olopatadine / mometasone) can raise the pressure in your eyes. This can sometimes lead to eye problems, like glaucoma or cataracts. Watch for changes like blind spots, blurry or cloudy vision, or depth perception problems.
If you have higher eye pressure, glaucoma, or cataracts, tell your eye specialist that you're using Ryaltris (olopatadine / mometasone). Also let them know if you notice any changes in your vision while using this medication.
Allergic reactions
Allergic reactions to Ryaltris (olopatadine / mometasone) are possible. Get medical help right away if you notice hives, rash, or swelling of your lips or tongue after using the medication. Also call 911 right away if you start wheezing or have trouble breathing.
Risk of infection
- Risk factors: Currently have an infection
The steroid in Ryaltris can make it harder for your body to fight infections and might make some infections worse. Use Ryaltris (olopatadine / mometasone) with caution if you have an infection. Tell your prescriber if you have tuberculosis (TB); a fungal, bacterial, viral, or parasitic infection; or a herpes infection in your eye. Your prescriber can help decide if the medication is safe for you.
Watch for any signs of infection while using Ryaltris (olopatadine / mometasone). This can include a fever, pain, aches, sore throat, or chills. If you think you have an infection, tell your prescriber so they can help treat it.
Altered stress hormone levels
- Risk factors: Using too much of Ryaltris (olopatadine / mometasone)
Using too much Ryaltris (olopatadine / mometasone) might affect your body's natural stress hormone called cortisol. When your cortisol levels are too high, it can lead to symptoms like weight gain or weak muscles. And when levels are too low, it can cause dizziness, tiredness, or loss of appetite.
Be sure to use Ryaltris (olopatadine / mometasone) only as directed. Don't use more sprays than prescribed. Talk to your prescriber if you notice any unusual symptoms while using this medication so they can check out what's going on.
Slowed growth in children
Ryaltris (olopatadine / mometasone) contains a steroid that might slow growth in children. The care team will monitor your child's growth during treatment. Talk to your child's prescriber if you have concerns about how this medication might affect their growth.
Ryaltris (olopatadine / mometasone) dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 240 metered sprays of 665mcg/25mcg/spray | 1 nasal spray | $274.43 | $274.43 |
How much does Ryaltris (olopatadine / mometasone) cost?
$274.43
Ryaltris (olopatadine / mometasone) contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Ryaltris (olopatadine / mometasone) will not be safe for you to take.
- Allergy to olopatadine or mometasone
What are alternatives to Ryaltris (olopatadine / mometasone)?
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