Key takeaways
Azelastine and Fluticasone are both nasal sprays used to treat allergy symptoms like a runny or stuffy nose. However, they belong to different medication classes. Azelastine is an antihistamine, while Fluticasone is a corticosteroid. Azelastine is available in prescription form as a generic nasal spray in two strengths (0.1% and 0.15%), while Fluticasone is available both over-the-counter and by prescription in various formulations. Azelastine is typically used twice a day, whereas Fluticasone is usually taken once a day. Azelastine can cause side effects like a bitter taste and sleepiness, while Fluticasone may lead to bitter taste, nosebleeds and, with long-term use, can slow growth in children. Azelastine may interact with alcohol and other sedatives, increasing drowsiness, while Fluticasone can raise the risk of infections and eye problems with prolonged use.
