Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Olopatadine (Pataday) and ketotifen (Zaditor) are both over-the-counter antihistamine eye drops used to treat allergy-related eye symptoms, but they have some differences. Olopatadine can be used by people as young as 2 years old, while ketotifen is for those 3 years and older. Olopatadine comes in different strengths and can be used once or twice daily depending on the formulation, whereas ketotifen is typically used twice daily. Olopatadine may work faster to relieve symptoms and has fewer side effects compared to ketotifen. Both medications require you to remove contact lenses before use and wait at least 10 minutes before putting them back in. Ketotifen should not be used for more than 3 days in a row without consulting a provider, while olopatadine can be used for year-round allergies. Both medications are available as lower-cost generics.
Olopatadine (Pataday)
Zaditor (ketotifen)
Olopatadine (Pataday)
Zaditor (ketotifen)
Summary of Olopatadine vs. Zaditor
Summary for Antihistamine
Olopatadine (Pataday) is an antihistamine over-the-counter (OTC) eye drop medication used to treat eye itching and redness from allergies. It's applied to the eyes, typically once or twice daily, depending on the strength. Some side effects of olopatadine (Pataday) include blurry vision and dry eye.
Summary for Antihistamine
Zaditor (ketotifen) is an antihistamine eye drop that's available over the counter for allergy-related itchy eyes. It works by blocking histamine and stopping your body from releasing chemicals that cause allergy symptoms. Adults and children can use Zaditor (ketotifen). The typical dosage is one drop into the affected eye(s) twice daily. Side effects can include headache, blurry vision, and dry eyes.