Zaditor (ketotifen) is an antihistamine eye drop that's available over the counter for allergy-related itchy eyes. It works by blocking histamine and stopping your body from releasing chemicals that cause allergy symptoms. Adults and children can use Zaditor (ketotifen). The typical dosage is one drop into the affected eye(s) twice daily. Side effects can include headache, blurry vision, and dry eyes.
Allergy-related itchy eyes
Zaditor (ketotifen) is an antihistamine and mast cell stabilizer. It works by stopping your body from reacting to substances that can irritate the eye.
More specifically, Zaditor (ketotifen) blocks histamine, a chemical that gets released in the body as a result of exposure to certain allergens. It also prevents other chemicals that cause allergy symptoms from being released from certain cells in your body called mast cells.
By blocking these chemicals, Zaditor (ketotifen) relieves itchy eyes from allergies.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
More common
Eye redness and swelling
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Burning or stinging of eyes
eyelid disorder
eye sensitivity to light
fever, tiredness, achiness, and sore throat
increase in size of pupils
tearing.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Works within 15 minutes to relieve itchy eyes
Available over the counter
Can use in children age 3 or older
Only need to use 1 drop twice a day
Won't treat an eye infection
Shouldn't be used for irritation caused by contact lenses
Can only be used for a short period of time
Need to take your contact lens out before placing the eye drop
Avoid getting the eye dropper tip dirty. If the tip gets dirty, bacteria could grow on it and get into your eye the next time you use the eye drops. This might raise your risk for an eye infection. Keep the dropper tip clean, and don't let it touch your eyelids, eyes, or any surfaces.
Remove your contact lenses before each time you use Zaditor (ketotifen). You can put them back in after 10 minutes. However, don't put your contacts back in if your eyes are red or irritated. Give your eyes a bit longer to rest because contacts might irritate them more.
After you place Zaditor (ketotifen) in your eye, keep your eye closed for a couple of minutes. This helps keep the medication in your eye.
If you're using other eye drop medications with Zaditor (ketotifen), wait at least 5 minutes after putting in the Zaditor (ketotifen) drops to put the drops of the other medication into the eye. This makes sure your eye fully absorbs each medication.
Don't use Zaditor (ketotifen) if the eye drop liquid has changed color or is cloudy.
Stop using Zaditor (ketotifen) and talk to your healthcare provider if you experience pain, irritation, worsening redness, or vision changes in your eye.
Talk to your healthcare provider if your symptoms don't improve or if they get worse within 3 days of using Zaditor (ketotifen).
Zaditor (ketotifen) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Those who wear soft contact lenses
Zaditor (ketotifen) isn't meant for treating eye irritation caused by wearing contact lens. Some formulations of Zaditor (ketotifen) contain a preservative that might be absorbed by soft contact lenses. If you wear soft contact lenses, remove them before you use Zaditor (ketotifen). You should wait at least 10 minutes after you use the eye drops to wear your contacts again.
Don't use Zaditor (ketotifen) if you're sensitive or allergic to one or more of the ingredients in the product. Read the ingredients label carefully.
Keep the applicator tip of Zaditor (ketotifen) clean. Don't let the tip touch your eyes, fingers, or other objects. This will helpf prevent eye infections.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
5ml of 0.025% | 1 eye dropper | $13.48 | $13.48 |
Adults and children 3 years and older: Put 1 drop in the affected eye(s) twice a day, every 8 to 12 hours.
Children under 3 years old: Ask your child's provider.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Eye itching or redness due to allergies (allergic conjunctivitis)
Temporary relief of allergy eye symptoms, such as itching and redness
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Abelson, M. B., et al. (2003). Efficacy of ketotifen fumarate 0.025% ophthalmic solution compared with placebo in the conjunctival allergen challenge model. Archives of Ophthalmology.
Ahn, J., et al. (2021). Binding affinity of benzalkonium chloride on contact lens surfaces and the effects on their physical properties. Colloids and Surfaces B: Biointerfaces.
Alcon Laboratories, Inc. (2023). Zaditor- ketotifen fumarate solution [package insert]. DailyMed.
Kidd, M., et al. (2003). Efficacy and safety of ketotifen eye drops in the treatment of seasonal allergic conjunctivitis. The British Journal of Ophthalmology.
Patel, D., et al. (2018). Topical olopatadine hydrochloride versus ketotifen fumarate for allergic conjunctivitis. Journal of Ophthalmic & Vision Research.
SafeMedication. (n.d.). How to use eye drops.
Weller, C. (n.d.). Mast cells. British Society for Immunology.
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