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Loteprednol vs. Nedocromil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Loteprednol (Lotemax) and nedocromil (Alocril) are both prescription eye medications, but they have some important differences. Loteprednol is a corticosteroid that treats various eye conditions, including dry eye disease, eye inflammation, and pain after eye surgery. It is also used for eye inflammation due to seasonal allergies. Nedocromil, on the other hand, is specifically used for itchy or watery eyes caused by allergies. While loteprednol is available in different forms like suspension, gel, and ointment, nedocromil is only available as an eye drop. Loteprednol can be used up to four times a day, whereas nedocromil is typically used twice daily. Both medications are available as a lower-cost generic. Common side effects of loteprednol include blurry vision and burning, while nedocromil may cause headaches and eye irritation. Both medications require careful handling to avoid contamination and should not be used with contact lenses.

Loteprednol

(Lotemax)

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Alocril

(nedocromil)

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Summary for Loteprednol

Prescription only

Loteprednol (Lotemax) is a steroid eye medication that comes in many strengths and forms to treat various eye conditions including recent eye surgery, dry eye, inflammation, and seasonal allergies.

Indications for Loteprednol

  • Dry eye disease
  • Eye inflammation conditions
  • Inflammation and pain after eye surgery
  • Eye inflammation due to seasonal allergies

Pros and Cons for Loteprednol

Pros

  • Applied directly where the pain or inflammation is
  • Causes fewer serious side effects than oral medications
  • Available as a suspension, gel, and ointment form

Cons

  • Slows healing and raises your risk of eye infection
  • May have to be used up to four times a day
  • Most forms are brand name only and may be expensive.

Common Side Effects for Loteprednol

  • Blurry vision
  • Burning after placing the drops into the eye
  • Itching
  • Feeling like there's something in your eye

Warnings for Loteprednol

  • HIGH EYE PRESSURE (GLAUCOMA)
  • CATARACTS
  • NEW OR WORSENED INFECTION
  • EYE INJURY OR DAMAGE
  • CONTACT LENS USE

Summary for Nedocromil

Prescription only

Alocril (nedocromil) is an eye drop for eye-related allergy symptoms, such as itchiness or watery eyes. Typically, you place 1 to 2 drops into your eyes twice daily. But it's not a first-choice option for allergy symptoms. Some common side effects of this medication include headaches and eye irritation.

Indications for Nedocromil

  • Itchy or watery eyes from allergy

Pros and Cons for Nedocromil

Pros

  • Relieves itchy and red eyes due to allergies
  • Can be combined with oral allergy medications
  • Can be used in children age 3 years and older

Cons

Common Side Effects for Nedocromil

  • Headache (40%)
  • Eye burning, stinging, or irritation (10-30%)
  • Unpleasant taste in the mouth (10-30%)
  • Stuffy nose (10-30%)

Warnings for Nedocromil

  • Contamination of dropper tip and solution
  • Avoid contact lenses

Prices with our coupons for Loteprednol vs. Nedocromil

Price Card Drug Icon
Loteprednol1 eye dropper / 5ml of 0.5%
$61.52$197.00
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Price Card Drug Icon
Alocril1 eye dropper / 5ml of 2%
$221.78-
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