Key takeaways:
The average retail cost of Ryaltris (olopatadine / mometasone) without insurance is $289.05 per bottle. Each bottle contains enough medication to last 1 month.
It’s common for Medicaid and commercial insurance plans to cover Ryaltris. But they may require a prior authorization or the completion of step therapy (trying other medications first). Ryaltris coverage is more limited with Medicare and Affordable Care Act plans.
If you have commercial insurance, you may be able to pay as little as $39 per bottle for Ryaltris. And anyone, regardless of insurance status, can use GoodRx to access the medication at an exclusive cash price of less than $60.
Save on related medications
There are dozens of options for managing seasonal allergy symptoms. For many people, nasal sprays are a convenient choice. And two types of nasal sprays (antihistamines and steroids) are first-choice allergy medications.
But for some people, one allergy nasal spray isn’t enough. In this case, a combination spray, such as Ryaltris (olopatadine / mometasone), may provide extra relief. But this prescription-only allergy medication may come with a higher cost, especially if you’re paying out of pocket.
So how much is Ryaltris without insurance? And how can you save on it?
How much does Ryaltris cost without insurance?
The average retail cost of 1 bottle of Ryaltris without insurance is $289.05. One bottle should last you for 1 month. The average price of 3 bottles (3 months) is $887.31.
Ryaltris comes as a nasal spray that provides olopatadine 665 mcg and mometasone 25 mcg in every spray. Each bottle contains 240 sprays (a 30-day supply). Ryaltris has no generic version available.
What factors affect the cost of Ryaltris?
Several factors affect the cost of Ryaltris, such as:
Location: Prescription costs vary in different areas of the country. For example, people in New Orleans typically pay more than people in Houston.
Pharmacy: Each pharmacy may charge slightly different amounts for medications (even those in the same neighborhood). Using GoodRx can help you compare costs before you fill your prescriptions.
Fill quantity: How many bottles of Ryaltris you get at one time also affects how much you’ll pay.
Insurance and discounts: Using insurance or applying discounts can help lower the cost of Ryaltris.
Does insurance cover Ryaltris?
Insurance coverage for Ryaltris varies, depending on the type of plan you have.
Nearly all Medicaid plans cover Ryaltris. But over 80% of those plans require you and your prescriber to submit a prior authorization before they’ll cover it. And over 20% of these plans require you to complete step therapy (trying other medications first).
About half of commercial plans also cover Ryaltris. It’s not common for plans to ask for a prior authorization. But close to 25% will require you to complete step therapy.
Medicare and Affordable Care Act (ACA) marketplace plans have more limited coverage of Ryaltris. Less than one-third of these plans cover the medication. But of the plans that do cover it, it’s less common than other plans for them to require prior authorization or the completion of step therapy.
It’s a good idea to check your plan’s summary of benefits and coverage and formulary (list of covered medications). This can help you determine if your insurance plan covers Ryaltris and how much it may cost you. For more information, you can also call the member services number on your prescription insurance card.
How different insurance plans cover Ryaltris
The table below details how likely it is that different insurance plans will cover Ryaltris. It also shows the likelihood that different plans will require a prior authorization or the completion of step therapy.
Insurance type | Enrollees covered for Ryaltris | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
27.2% | 19.7% | 6.7% | |
Commercial plans (excluding ACA plans) | 50.7% | 12.8% | 23.5% |
Medicare (Medicare Advantage and Part D plans) | 33.1% | 0.2% | 7.7% |
Medicaid, including state-run and managed care plans | 99.5% | 83.6% | 22.3% |
Source: Managed Markets Insight & Technology, LLC™, as of January 10, 2026 (See methodology below.)
If your insurance doesn’t cover Ryaltris, try these options:
Use GoodRx to access an exclusive deal to help lower your prescription cost to less than $60.
Request a formulary exception from your insurance company. If your request is denied, you have the right to appeal the decision to seek coverage.
Ask your prescriber about alternatives. There are other allergy medications that your insurance may offer better coverage for or that have lower-cost generics.
When it’s time for open enrollment, compare different health insurance plans to find one that provides better coverage for what you need.
Ways to save on Ryaltris
Below are four ways to save on Ryaltris with or without insurance.
1. Pay as low as $39 with the Ryaltris Savings Card
If you have commercial insurance, you may be able to pay as low as $39 per bottle using a manufacturer copay card (the Ryaltris Savings Card). This card has a maximum savings of $60 per bottle.
To be eligible for the $39 offer with the Ryaltris Savings Card, you must:
Have commercial insurance that covers Ryaltris
Not have federal- or state-funded insurance, such as Medicare or Medicaid
Be a legal resident of the U.S. or Puerto Rico
You can download the card online. For more information, call 1-800-631-2174.
2. Pay less than $60 with a GoodRx coupon
Anyone, regardless of insurance status, can use GoodRx to access Ryaltris at an exclusive cash price of less than $60. This can be helpful if you don’t have insurance or your insurance doesn’t cover Ryaltris.
To get a GoodRx discount for Ryaltris:
Visit the GoodRx website or download the app.
Type “Ryaltris” in the search box, and click or tap “Start saving.”
Choose your quantity.
Have your discount information sent to you via text or email, or print it. If you’re using the app, keep the discount ready on your phone’s screen, or save it to your digital wallet.
Alert the pharmacy staff that you’ll be using a GoodRx discount before they fill your prescription to help prevent checkout delays.
3. Ask about 90-day supplies
Some pharmacies and insurance plans offer discounts when you fill a 3-month supply instead of a 1-month supply. This can lower your monthly Ryaltris costs over time. Plus, it reduces the number of trips you make to the pharmacy.
What’s more, some insurance providers offer additional discounts if you use their preferred mail-order pharmacies to fill 3-month supplies. Check with your insurance plan and pharmacy to see if they offer discounts for filling prescriptions in bulk.
4. Tap into your HSA, FSA, or HRA
If you have a health savings account (HSA), a flexible spending account (FSA), or a health reimbursement arrangement (HRA), you can use these funds to pay for your Ryaltris prescription. This can help you save money through tax savings.
Keep in mind that FSAs have an expiration date. So you’ll need to use your funds before that date. HSAs and HRAs typically roll over, so you can save those funds to use later.
The bottom line
The average cost of Ryaltris (olopatadine / mometasone) without insurance is $289.05 per bottle. Each bottle should provide a 1-month supply of medication.
Nearly all Medicaid plans and about half of all commercial plans cover Ryaltris. But you may need to submit a prior authorization or complete step therapy before they’ll cover it. Medicare and Affordable Care Act marketplace plans have more limited coverage of Ryaltris.
If you have commercial insurance, you may be able to pay as little as $39 per bottle using the Ryaltris Savings Card. And anyone, regardless of insurance status, can use GoodRx to access Ryaltris at an exclusive cash price of less than $60.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of January 2026.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
Hikma Specialty USA. (n.d.). Savings and support to help patients start and stay on Ryaltris®.
Hikma Specialty USA. (2026). Ryaltris- olopatadine hydrochloride and mometasone furoate spray, metered [package insert]. DailyMed.
Medicaid.gov. (n.d.). Managed care. Centers for Medicare & Medicaid Services.
Seidman, M. D., et al. (2015). Clinical practice guideline: Allergic rhinitis. Otolaryngology—Head and Neck Surgery.
