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Compare Bimzelx vs. Cosentyx

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bimzelx (bimekizumab) and Cosentyx (secukinumab) are both medications used to treat plaque psoriasis, psoriatic arthritis, and hidradenitis suppurativa, among other conditions. And they both belong to the interleukin inhibitor medication class. However, they have some differences. Bimzelx is specifically an interleukin antagonist that blocks IL-17A and IL-17F, while Cosentyx is an IL-17 inhibitor. Bimzelx is typically injected every month or every other month, while Cosentyx is injected weekly for the first five weeks and then monthly. Both medications are available as prefilled syringes or pens, but Cosentyx can also be given as an infusion. Common side effects of Bimzelx include upper respiratory infections and oral thrush, while Cosentyx may cause common cold symptoms and diarrhea. Both medications can increase the risk of infections due to their effects on the immune system.

  • Bimzelx (bimekizumab)
    Cosentyx (secukinumab)
  • Bimzelx (bimekizumab)
    Cosentyx (secukinumab)

  • Summary of Bimzelx vs. Cosentyx

    Summary for Interleukin antagonist
    Prescription only

    Bimzelx (bimekizumab or bimekizumab-bkzx) is an injection that's used to treat several inflammatory conditions in adults. They include plaque psoriasis, psoriatic arthritis, and hidradenitis suppurativa, to name a few. It's a type of monoclonal antibody called an interleukin antagonist. It works to reduce inflammation in the body. Bimzelx (bimekizumab) comes in prefilled autoinjectors or prefilled syringes. You inject the medication under the skin either every month or every other month. It can cause side effects like upper respiratory infections.

    Summary for Interleukin 17 (IL-17) antagonist
    Prescription only

    Cosentyx (secukinumab) is an injectable medication that treats many inflammatory conditions. This includes plaque psoriasis (PsO), psoriatic arthritis (PsA), and hidradenitis suppurativa (HS), among others. It works as an interleukin 17 antagonist to lower inflammation in the body. Some people might need a few starter doses. But it's usually injected under the skin once a month. You can use the prefilled syringes, Sensoready Pens, or UnoReady Pens to inject. For some conditions, the medication can also be given as an infusion into the vein at a clinic. The dosing depends on your age, health condition, and treatment plan. Side effects include upper respiratory tract infections and upset stomach.

  • Indications of Bimzelx vs. Cosentyx

    Indications for
    •Moderate-to-severe plaque psoriasis
    •Psoriatic arthritis
    •Non-radiographic axial spondyloarthritis
    •Ankylosing spondylitis
    •Moderate-to-severe hidradenitis suppurativa
    Indications for
    •Moderate-to-severe plaque psoriasis (PsO) in people 6 years and older
    •Psoriatic arthritis (PsA) in people 2 years and older
    •Ankylosing spondylitis (AS) in people 12 years and older
    •Non-radiographic axial spondyloarthritis (nr-axSpA) in adults
    •Moderate-to-severe hidradenitis suppurativa (HS) in people 12 years and older
    •Enthesitis-related arthritis in children 4 years and older

  • Pros and Cons of Bimzelx vs. Cosentyx

    Pros and Const for Interleukin antagonist
    Pros
    •Dosing schedule is either every month or every other month, so it's convenient for most people
    •An option for plaque psoriasis if topical medications have stopped working
    •Available as prefilled autoinjectors and prefilled syringes
    Cons
    •Can cause injection reactions, such as pain, bruising, and swelling
    •Might raise the risk of infections
    •Unknown if safe during pregnancy or while breastfeeding
    Pros and Const for Interleukin 17 (IL-17) antagonist
    Pros
    •Generally injected once a month (might need a few starter doses)
    •Available as prefilled syringes or pens for at-home injections
    •Okay for children of certain ages to use (depends on the condition being treated and with the exception of nr-axSpA)
    •Few side effects
    Cons
    •Must be given as an injection
    •Might raise the risk of infections
    •Might cause flare-ups in people with ulcerative colitis or Crohn's disease
    •Sensoready pens and prefilled syringes might not be a good option for people with a latex allergy

  • Common Side Effects of Bimzelx vs. Cosentyx

    Common Side Effects for
    •Upper respiratory tract infection (runny nose, sore throat; 15%)
    •Oral thrush (9%)
    •Headache (3%)
    •Injection site reactions (redness, pain, swelling, bruising; 3%)
    •Fungal skin infections (3%)
    Common Side Effects for
    •Common cold (11%)
    •Diarrhea (4%)
    •Upper respiratory tract infections (3%)

  • Warnings of Bimzelx vs. Cosentyx

    Common Side Effects for
    •Suicidal thoughts or behavior
    •Risk of infections
    •Liver problems
    •Inflammatory bowel disease
    •Interaction with vaccines
    Common Side Effects for
    •Risk of infection
    •Caution when getting vaccines
    •Eczema-like skin reaction
    •Allergic reaction
    •Inflammatory bowel disease

  • Prices with our coupons for Bimzelx vs. Cosentyx

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