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Antifolates

Antifolates are used to treat psoriasis by slowing the growth of cells that cause scaly skin. They can also treat rehumatoid arthritis and juvenile arthritis by reducing inflammation in the joints. They are also used to treat many types of cancer such as leukemia, breast cancer, lung cancer, non-Hodgkin's lymphoma, bone cancer, and mesothelioma by slowing down the growth of cells that cause cancer.

Why are antifolates prescribed?

  1. Leukemia (25%)
  2. Psoriasis (25%)
  3. Non-Hodgkin Lymphoma (25%)
  4. Rheumatoid Arthritis (25%)
  5. Lung Cancer (0%)
  6. Mesothelioma (0%)

Key takeaways

Antifolates are used to treat various types of cancer, including breast cancer, non-small cell lung cancer, and Non-Hodgkin lymphoma. They also have other uses, such as managing rheumatoid arthritis and psoriasis. Antifolates work by slowing down the growth of cancer cells and reducing inflammation in autoimmune disorders. These medications come in different forms, including oral pills, oral liquids, and injections. Examples include methotrexate (Trexall, Rasuvo, Xatmep, Jylamvo, Otrexup) and pemetrexed (Alimta, Pemfexy).

Prices for popular Antifolates medications
Viewing 13 of 13 medications
Methotrexate (Rheumatrex) is a moderately priced chemotherapy drug used to treat cancer including breast cancer, leukemia, and lymphoma. It can also be used to treat psoriasis and certain kinds of arthritis. It is more popular than comparable drugs. It is only available as a generic drug; all brands have been discontinued. Generic methotrexate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Trexall

as low as$183
METHOTREXATE treats autoimmune conditions, such as arthritis and psoriasis. It works by decreasing inflammation, which can reduce pain and prevent long-term injury to the joints and skin. It may also be used to treat some types of cancer. It works by slowing down the growth of cancer cells.
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Reditrex

as low as$323
Reditrex (methotrexate) is used to treat psoriasis and rheumatoid arthritis. Reditrex is only available as a brand drug. Reditrex is covered by some Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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Xatmep

as low as$325
METHOTREXATE treats autoimmune conditions, such as arthritis and psoriasis. It works by decreasing inflammation, which can reduce pain and prevent long-term injury to the joints and skin. It may also be used to treat some types of cancer. It works by slowing down the growth of cancer cells.
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Otrexup

as low as$530
Otrexup (methotrexate) is a cytotoxic drug that also suppresses the immune system. It is used to treat psoriasis and rheumatoid arthritis. It is slightly more popular than comparable drugs. There are currently no generic alternatives for Otrexup.

GoodRx has partnered with InsideRx and Antares Pharma to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Otrexup is not covered by most Medicare and insurance plans.
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Rasuvo

as low as$533
Rasuvo (methotrexate) is used to treat psoriasis and rheumatoid arthritis. It is slightly more popular than comparable drugs. There is currently no generic alternative for Rasuvo.

GoodRx has partnered with InsideRx and Medac Pharma to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Rasuvo is covered by most Medicare and insurance plans.
Pemetrexed Dipotassium is part of the Antifolates class and treats Lung Cancer and Mesothelioma. Antifolates are used to treat psoriasis by slowing the growth of cells that cause scaly skin. They can also treat rehumatoid arthritis and juvenile arthritis by reducing inflammation in the joints. They are also used to treat many types of cancer such as leukemia, breast cancer, lung cancer, non-Hodgkin's lymphoma, bone cancer, and mesothelioma by slowing down the growth of cells that cause cancer. Pemetrexed Dipotassium is only available as a generic drug.
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Axtle

as low as$763
Axtle is part of the Antifolates class and treats Lung Cancer and Mesothelioma. Antifolates are used to treat psoriasis by slowing the growth of cells that cause scaly skin. They can also treat rehumatoid arthritis and juvenile arthritis by reducing inflammation in the joints. They are also used to treat many types of cancer such as leukemia, breast cancer, lung cancer, non-Hodgkin's lymphoma, bone cancer, and mesothelioma by slowing down the growth of cells that cause cancer. Axtle is only available as a brand name drug.
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Jylamvo

as low as$789
METHOTREXATE treats autoimmune conditions, such as arthritis and psoriasis. It works by decreasing inflammation, which can reduce pain and prevent long-term injury to the joints and skin. It may also be used to treat some types of cancer. It works by slowing down the growth of cancer cells.
PEMETREXED treats some types of cancer. It works by slowing down the growth of cancer cells.
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Pemfexy

as low as$4,268
PEMETREXED treats some types of cancer. It works by slowing down the growth of cancer cells.
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Folotyn

as low as$6,503
PRALATREXATE treats lymphoma. It works by slowing down the growth of cancer cells.
PEMETREXED treats some types of cancer. It works by slowing down the growth of cancer cells.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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