Axtle is part of the Antifolates class and treats Lung Cancer and Mesothelioma. Antifolates are used to treat psoriasis by slowing the growth of cells that cause scaly skin. They can also treat rehumatoid arthritis and juvenile arthritis by reducing inflammation in the joints. They are also used to treat many types of cancer such as leukemia, breast cancer, lung cancer, non-Hodgkin's lymphoma, bone cancer, and mesothelioma by slowing down the growth of cells that cause cancer. Axtle is only available as a brand name drug.