Aristada

• Risk factors: Older adults with dementia-related psychosis

Older adults who also have dementia sometimes have some symptoms of schizophrenia, like hallucinations and delusions. This is called dementia-related psychosis, and it should not be treated with Aristada (aripiprazole lauroxil). If Aristada (aripiprazole lauroxil) is used for dementia-related psychosis, it can cause death. The cause of death is typically from heart problems, stroke, or infections. Let your provider know if you or your loved one has dementia before starting Aristada (aripiprazole lauroxil).

• Risk factors: Taking antipsychotic medications

Aristada (aripiprazole lauroxil) can cause neuroleptic malignant syndrome (NMS), which is a rare but serious condition that can lead to death. Be careful using Aristada (aripiprazole lauroxil) if you're also on other medications that might cause NMS. Symptoms include a very high fever, stiff muscles, problems thinking clearly, very fast or uneven heartbeat, and sweating. Stop taking Aristada (aripiprazole lauroxil) and get medical attention right away if you experience these symptoms.

• Risk factors: Older adults | Female and 65 years or older | Higher than recommended doses of Aristada (aripiprazole lauroxil) | Taking Aristada (aripiprazole lauroxil) for a long time

Aristada (aripiprazole lauroxil) can cause uncontrolled and possibly permanent muscle movements in the tongue, face, mouth, lips, neck, hands, arms, legs, and feet (tardive dyskinesia). To lower your risk of tardive dyskinesia, use the lowest dose for your symptoms. Get medical help right away if you notice any unusual movements you can't control.

• Risk factors: History of diabetes | History of high cholesterol | Obesity

Aristada (aripiprazole lauroxil) can raise your blood sugar, sometimes to dangerous levels resulting in coma or death. Let your provider know if you have symptoms of high blood sugar, such as feeling very hungry or thirsty, urinating more often, stomach pain, weakness, or fruity-smelling breath.

Aristada (aripiprazole lauroxil) can also cause high cholesterol and weight gain. Your provider might check your weight and order blood tests regularly to make sure your blood sugar, cholesterol, and weight aren't too high.

Aristada (aripiprazole lauroxil) can make it difficult for you to think through your actions and control your behavior. It can lead to strong urges for certain behaviors, such as gambling, eating, shopping, or sex. Because these behaviors can cause harm to yourself or others, your provider might lower your dose or stop the medication. If you or your loved ones notice a change in behavior, let your provider know.

• Risk factors: Starting Aristada (aripiprazole lauroxil) for the first time | Recent rise in Aristada (aripiprazole lauroxil) dose | Older adults | Not enough fluids in your body | History of heart problems | History of low blood pressure | Taking medications that lower blood pressure

Aristada (aripiprazole lauroxil) can cause sleepiness, dizziness, difficulty keeping your balance, and drops in blood pressure when you sit up or stand too quickly. This can result in fainting and falling, leading to fractures or other injuries. Sit up or stand up slowly, especially during the first few days after you start Aristada (aripiprazole lauroxil) or when your provider raises your dose. Your risk of falls is higher if you have heart problems or if you don't have enough fluids in your body. Talk to your healthcare provider if you continue to experience dizziness while taking Aristada (aripiprazole lauroxil).

• Risk factors: History of low white blood cell counts | Taking other medications that lower white blood cell counts

Aristada (aripiprazole lauroxil) can lower the amount of white blood cells in your body and put you at higher risk for serious infection. You might need to get lab work done regularly to make sure your white blood cell count is healthy. If the levels are too low, your provider might stop your medication. Talk to your provider right away if you experience symptoms of an infection, such as fever, weakness, or sore throat, while taking this medication.

• Risk factors: History of seizures | Health conditions that raise the risk of seizures | Age 65 years or older

Aristada (aripiprazole lauroxil) can make you more likely to have seizures. Before starting this medication, let your provider know if you have a history of seizures or have a medical condition that puts you at risk of getting seizures.