Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Haldol vs. Aristada

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Haldol (haloperidol) and Aristada (aripiprazole lauroxil) are both injectable medications used to treat schizophrenia, but they have some key differences. Haldol is a typical antipsychotic that works by blocking dopamine, while Aristada is an atypical antipsychotic that balances both dopamine and serotonin. Haldol is usually given monthly, but it can also be administered as a short-acting injection in hospital settings for agitation. Aristada, on the other hand, can be given every 1 to 2 months, isn't short-acting, and requires you to tolerate Abilify (aripiprazole) tablets first. Haldol has a higher risk of movement-related side effects, such as rigid muscles and tremors, whereas Aristada can cause high blood sugar and weight gain. Additionally, Haldol is available as a lower-cost generic, while Aristada is only available as a brand medication and can be more expensive. Both medications should not be used in older adults with dementia-related psychosis due to a higher risk of death.

  • Haloperidol injection
    Aristada (aripiprazole lauroxil)
  • Haloperidol injection
    Aristada (aripiprazole lauroxil)

  • Summary of Haldol vs. Aristada

    Summary for Typical antipsychotic
    Prescription only

    Haloperidol injection is an antipsychotic medication that's used to treat schizophrenia. It's a long-acting injection that's given into the muscles monthly by a healthcare provider. It's also available as a shorter-acting injection that's typically given in a hospital setting to people who are experiencing agitation related to schizophrenia. The most common side effects of haloperidol injection are movement-related side effects, such as rigid muscles, tremors, and trouble speaking.

    Summary for Atypical antipsychotic
    Prescription only

    Aristada (aripiprazole lauroxil) is used to improve mood, thoughts, and behaviors in adults who have schizophrenia. It's a long-acting medication that's injected into your muscle every 1 to 2 months by your healthcare provider. It's only used in people who can tolerate Abilify (aripiprazole) oral tablets.

  • Indications of Haldol vs. Aristada

    Indications for
    •Schizophrenia
    Indications for
    •Schizophrenia

  • Pros and Cons of Haldol vs. Aristada

    Pros and Const for Typical antipsychotic
    Pros
    •Typically given monthly
    •Low risk for weight gain, compared to some other antipsychotics
    •Available as a lower-cost, generic medication
    Cons
    •Needs to be injected
    •Higher risk of movement-related side effects compared to atypical antipsychotics
    •Can't be used in children
    Pros and Const for Atypical antipsychotic
    Pros
    •Can be given up to once every 2 months
    •Good option for people who have a hard time taking medications by mouth
    •Has fewer side effects compared to some other antipsychotic medications
    •Patient assistance programs are available to help lower the cost
    Cons
    •Can cause high blood sugar and weight gain
    •Must be injected in the muscle at your healthcare provider's office
    •Can cause soreness or pain at the injection site
    •Not recommended for use during pregnancy or breastfeeding
    •Can be expensive because it's only available as a brand medication

  • Common Side Effects of Haldol vs. Aristada

    Common Side Effects for
    •Stiff or rigid muscles, tremors, trouble speaking, and other parkinsonism symptoms (31%)
    Common Side Effects for
    •Restlessness (11%)
    •Unusual and uncontrollable muscle movements or muscle spasms (5-7%)

  • Warnings of Haldol vs. Aristada

    Common Side Effects for
    •Higher risk of death in older people with dementia-related psychosis
    •Life-threatening abnormal heart rhythm (QT prolongation)
    •Difficulty controlling body movements
    •Neuroleptic malignant syndrome (NMS)
    •Higher risk of falls
    •Pneumonia
    •Low white blood cell counts
    •Harm to unborn babies
    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Neuroleptic malignant syndrome (NMS)
    •Difficulty controlling muscle movements (tardive dyskinesia)
    •High blood sugar, high cholesterol, and weight gain
    •Impulsive behavior
    •Higher risk of falls
    •Higher risk of infections
    •Seizures

  • Prices with our coupons for Haldol vs. Aristada

    Learn more about Haloperidol injection
    Learn more about Aristada

Compare other Schizophrenia drugs

Clozaril vs HaldolHaldol vs AbilifyHaldol vs AristadaHaldol vs AtivanHaldol vs ChlorpromazineHaldol vs FanaptHaldol vs Fluphenazine DecanoateHaldol vs GeodonHaldol vs InvegaHaldol vs LoxapineHaldol vs NeurontinHaldol vs PerphenazineHaldol vs RexultiHaldol vs RisperdalHaldol vs SaphrisHaldol vs SeroquelHaldol vs ThioridazineHaldol vs ThiothixeneHaldol vs ThorazineHaldol vs TrifluoperazineHaldol vs XanaxHaldol vs ZyprexaClozaril vs RisperdalCompazine vs ThorazineInvega vs ClozarilLoxapine vs ClozarilPerphenazine vs ClozarilSeroquel vs ClozarilThiothixene vs ClozarilTrifluoperazine vs Clozaril
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.