Key takeaways
Haloperidol (Haldol) and risperidone (Risperdal) are both antipsychotic medications, but they belong to different classes. Haloperidol is a typical antipsychotic, while risperidone is an atypical antipsychotic. Haloperidol is mainly used to treat schizophrenia and is available as oral forms, as well as a long-acting injection given monthly or a short-acting injection for acute agitation. Risperidone is also available in oral and injectable forms, and is used to treat schizophrenia, bipolar disorder, and irritability associated with autism. Both medications can cause movement-related side effects, such as rigid muscles and tremors, as well as weight gain and sleepiness. Both medications can be used in children. Both medications have serious risks, including a higher risk of death in older adults with dementia-related psychosis and the potential for neuroleptic malignant syndrome.
