Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Haldol vs. Thiothixene

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Haloperidol (Haldol) and thiothixene (Navane) are both typical antipsychotics used to treat schizophrenia, but they have some key differences. Haloperidol is available as an oral tablet, oral liquid, and injection, either long-acting (monthly) or short-acting (for hospital use), while thiothixene is taken orally. Both medications can cause movement-related side effects like rigid muscles and tremors. Thiothixene can be taken by people as young as 12, whereas haloperidol can be used in children as young as age 3 years. Both medications carry risks for older adults with dementia-related psychosis and can cause serious side effects like neuroleptic malignant syndrome.

  • Haloperidol injection
    Thiothixene
  • Haloperidol injection
    Thiothixene

  • Summary of Haldol vs. Thiothixene

    Summary for Typical antipsychotic
    Prescription only

    Haloperidol injection is an antipsychotic medication that's used to treat schizophrenia. It's a long-acting injection that's given into the muscles monthly by a healthcare provider. It's also available as a shorter-acting injection that's typically given in a hospital setting to people who are experiencing agitation related to schizophrenia. The most common side effects of haloperidol injection are movement-related side effects, such as rigid muscles, tremors, and trouble speaking.

    Summary for First-generation (typical) antipsychotic
    Prescription only

    Thiothixene is used to treat schizophrenia in people ages 12 years and older. It belongs to a drug class known as typical antipsychotics. This medication comes as a oral capsule and it's typically taken 2-3 times a day. Some of the more common side effects of this medication include drowsiness, restlessness, and uncontrolled body movement. Thiothixene is only available as a generic medication. Brand name Navane has been discontinued.

  • Indications of Haldol vs. Thiothixene

    Indications for
    •Schizophrenia
    Indications for
    •Schizophrenia in people ages 12 years and older

  • Pros and Cons of Haldol vs. Thiothixene

    Pros and Const for Typical antipsychotic
    Pros
    •Typically given monthly
    •Low risk for weight gain, compared to some other antipsychotics
    •Available as a lower-cost, generic medication
    Cons
    •Needs to be injected
    •Higher risk of movement-related side effects compared to atypical antipsychotics
    •Can't be used in children
    Pros and Const for First-generation (typical) antipsychotic
    Pros
    •Taken by mouth
    •Can be taken by children as young as 12 years old
    •Dose can be adjusted based on your response
    Cons
    •Might need to take up to 3 times a day
    •Can cause low white blood cell counts so might need to have regular blood tests done
    •More likely to cause movement-related problems than atypical antipsychotics

  • Common Side Effects of Haldol vs. Thiothixene

    Common Side Effects for
    •Stiff or rigid muscles, tremors, trouble speaking, and other parkinsonism symptoms (31%)
    Common Side Effects for
    •Drowsiness
    •Trouble sleeping
    •Restlessness
    •Uncontrollable body movement

  • Warnings of Haldol vs. Thiothixene

    Common Side Effects for
    •Higher risk of death in older people with dementia-related psychosis
    •Life-threatening abnormal heart rhythm (QT prolongation)
    •Difficulty controlling body movements
    •Neuroleptic malignant syndrome (NMS)
    •Higher risk of falls
    •Pneumonia
    •Low white blood cell counts
    •Harm to unborn babies
    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Difficulty controlling muscle movements (tardive dyskinesia)
    •Abnormal and prolonged muscle contractions (dystonia)
    •Neuroleptic malignant syndrome (NMS)
    •Seizures
    •Drowsiness and sleepiness
    •Low white blood cell count
    •Vision changes
    •High prolactin levels

  • Prices with our coupons for Haldol vs. Thiothixene

    Learn more about Haloperidol injection
    Learn more about Thiothixene

Compare other Schizophrenia drugs

Clozaril vs HaldolHaldol vs AbilifyHaldol vs AristadaHaldol vs AtivanHaldol vs ChlorpromazineHaldol vs FanaptHaldol vs Fluphenazine DecanoateHaldol vs GeodonHaldol vs InvegaHaldol vs LoxapineHaldol vs NeurontinHaldol vs PerphenazineHaldol vs RexultiHaldol vs RisperdalHaldol vs SaphrisHaldol vs SeroquelHaldol vs ThioridazineHaldol vs ThiothixeneHaldol vs ThorazineHaldol vs TrifluoperazineHaldol vs XanaxHaldol vs ZyprexaFluphenazine vs TrifluoperazineLoxapine vs TrifluoperazinePerphenazine vs TrifluoperazineThiothixene vs TrifluoperazineTrifluoperazine vs AbilifyTrifluoperazine vs ClozarilTrifluoperazine vs GeodonTrifluoperazine vs Risperdal
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.