Key takeaways
Haldol (haloperidol) and Abilify (aripiprazole) are both antipsychotic medications, but they belong to different classes. Haldol is a typical antipsychotic, while Abilify is an atypical antipsychotic. Haldol is primarily used to treat schizophrenia and is available as a long-acting injection given monthly or as a short-acting injection for acute agitation. In contrast, Abilify treats a wider range of conditions, including schizophrenia, bipolar I disorder, depression (as an add-on treatment), Tourette syndrome, and irritability associated with autism. Abilify is available in various forms, such as tablets, oral solutions, orally disintegrating tablets, and injectable forms, and can be used in children as young as 6 years old for certain conditions. Both medications can cause movement-related side effects, weight gain, and high blood sugar, but Abilify can also cause cholesterol issues. Both medications can cause serious side effects like neuroleptic malignant syndrome and have a higher risk of death in older adults with dementia-related psychosis. Haldol also has a risk for serious withdrawal symptoms if you suddenly stop taking it.
