Key takeaways
Latuda (lurasidone) and Invega (paliperidone) are both atypical antipsychotics, but they have some key differences. Latuda is used to treat schizophrenia in people aged 13 and older and bipolar depression in people aged 10 and older. Invega, on the other hand, is used for schizophrenia and schizoaffective disorder in adults and adolescents aged 12 and older. Latuda is taken as a tablet once a day with food, while Invega is an extended-release tablet that can be taken with or without food. Latuda is less likely to cause weight gain compared to other antipsychotics, whereas Invega can cause weight gain and higher blood sugar levels. Both medications can cause sleepiness and movement problems, but Latuda is noted for causing sleepiness in up to 17% of users, while Invega can cause abnormal muscle movements in up to 40% of users. Both Latuda and Invega are available in brand and generic forms.
