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Compare Latuda vs. Geodon

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Latuda (lurasidone) and Geodon (ziprasidone) are both atypical antipsychotics used to treat schizophrenia and bipolar disorder, but they have some key differences. Latuda is available only as an oral tablet, while Geodon comes in both oral and injectable forms. Latuda is typically taken once a day with food, whereas Geodon needs to be taken twice daily with food. Latuda is approved for use in children as young as 10 for bipolar depression and 13 for schizophrenia, while Geodon is only approved for adults. Both medications can cause sleepiness, but Latuda is less likely to cause weight gain compared to Geodon. Geodon has a higher risk of causing heart rhythm problems, so it’s not suitable for people with certain heart conditions. Additionally, Latuda is less likely to cause noticeable weight gain and may even lead to weight loss in some cases.

  • Latuda (lurasidone)
    Ziprasidone (Geodon)
  • Latuda (lurasidone)
    Ziprasidone (Geodon)

  • Summary of Latuda vs. Geodon

    Summary for Atypical antipsychotic
    Prescription only

    Latuda (lurasidone) is an atypical antipsychotic that's used to treat schizophrenia in adults and children age 13 years and older. It can also be used for treating depression from bipolar disorder in adults and children age 10 years and older. Latuda (lurasidone) is a tablet that's taken by mouth once per day. The most common side effect is sleepiness, and the medication is less likely to cause weight gain compared to other antipsychotics.

    Summary for Atypical antipsychotic
    Prescription only

    Ziprasidone (Geodon) is an atypical antipsychotic medication used to treat bipolar I disorder and schizophrenia in adults. It works by balancing the levels of certain chemicals in the brain, like dopamine and serotonin. Ziprasidone (Geodon) is taken by mouth, typically twice daily. It's also available as an injection that's given into the muscles by a healthcare provider to treat agitation in schizophrenia. Some common side effects of ziprasidone (Geodon) include uncontrolled body movements, sleepiness, and nausea.

  • Indications of Latuda vs. Geodon

    Indications for
    •Schizophrenia in people age 13 years and older
    •Depression from bipolar disorder in people age 10 years and older
    •Add-on therapy to lithium (Lithobid) or divalproex (Depakote) for depression from bipolar disorder in adults
    Indications for
    •Bipolar I disorder
    •Schizophrenia

  • Pros and Cons of Latuda vs. Geodon

    Pros and Const for Atypical antipsychotic
    Pros
    •Works well for depression from bipolar disorder and schizophrenia
    •Only need to take it once a day
    •Can use in adults and children
    •Less likely to affect your weight than other antipsychotics
    Cons
    •Can take several weeks before you feel the full effects
    •Can make you feel sleepy
    •Can cause movement problems
    •Only available as a tablet
    Pros and Const for Atypical antipsychotic
    Pros
    •Taken by mouth
    •Less likely to weight gain than other similar medications
    •Available as a lower-cost generic medication
    Cons
    •Taken twice daily
    •Might take several weeks before you feel the full benefits of this medication
    •Must be taken with food

  • Common Side Effects of Latuda vs. Geodon

    Common Side Effects for
    •Sleepiness
    •Nausea
    •Difficulty moving or slow movements
    •Can't stay still
    Common Side Effects for
    •Uncontrolled body movements (14%)
    •Sleepiness (14%)
    •Nausea (10%)
    •Constipation (9%)
    •Indigestion (8%)
    •Restlessness (8%)
    •Dizziness (8%)
    •Respiratory tract infection (8%)

    Note: Side effects listed were reported by people who took ziprasidone for schizophrenia in a clinical study

  • Warnings of Latuda vs. Geodon

    Common Side Effects for
    •Worsening depression, suicidal thoughts, and unusual behavior
    •Higher risk of death in older adults with dementia-related psychosis
    •Neuroleptic malignant syndrome
    •Difficulty controlling muscle movements (tardive dyskinesia)
    •Changes in weight, blood sugar levels, and cholesterol levels
    •High prolactin levels
    •Changes in blood pressure and risk of falls
    •Risk of infection (from low white blood cell count)
    •Difficulty concentrating and extreme sleepiness
    •Seizures
    •Triggering a manic episode
    •Side effects affecting the nervous system in people with Parkinson's disease or Lewy body dementia
    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Risk of suicidal thoughts and behavior
    •Difficulty controlling muscle movements (tardive dyskinesia)
    •Weight gain, higher blood sugar, and higher cholesterol levels
    •Neuroleptic malignant syndrome
    •Difficulty concentrating and extreme sleepiness
    •Changes in blood pressure and higher risk of falls
    •Risk of infection (from low white blood cell count)
    •Seizures
    •Serious skin reaction
    •Prolonged and painful erection
    •High prolactin levels
    •Heart rhythm problems

  • Prices with our coupons for Latuda vs. Geodon

    Learn more about Latuda
    Learn more about Ziprasidone

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