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Lurasidone Coupon - Lurasidone 40mg tablet

lurasidone

Generic Latuda
Used for Bipolar Disorder, Schizophrenia
Used for Bipolar Disorder, Schizophrenia

Latuda (lurasidone) is an atypical antipsychotic that's used to treat schizophrenia in adults and children age 13 years and older. It can also be used for treating depression from bipolar disorder in adults and children age 10 years and older. Latuda (lurasidone) is a tablet that's taken by mouth once per day. The most common side effect is sleepiness, and the medication is less likely to cause weight gain compared to other antipsychotics.

Last reviewed on October 31, 2023
basics-icon

What is Latuda (lurasidone)?

What is Latuda (lurasidone) used for?

How Latuda (lurasidone) works

Latuda (lurasidone) is an atypical antipsychotic. It's not completely known how the medication works. But it's thought to work by balancing out the levels of certain chemicals (dopamine and serotonin) in your brain to help control your thoughts, mood, and behaviors.

When does Latuda (lurasidone) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsLatuda
Drug ClassAtypical antipsychotic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Latuda (lurasidone) essentials

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Avg retail price
$1040.080
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$1040.08
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What are the side effects of Latuda (lurasidone)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sleepiness
  • Nausea
  • Difficulty moving or slow movements
  • Can't stay still

Other Side Effects

  • Dizziness
  • Stomach pain
  • Diarrhea
  • Vomiting
  • Lower appetite
  • Blurry vision
  • Rash
  • Itching
  • High blood pressure
  • Fast heart rate
  • Trouble sleeping
  • Infection

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Neuroleptic malignant syndrome: fever, sweating, stiff muscles, confusion, not aware of your surroundings, fast or irregular heartbeat
  • Stroke: numbness or weakness typically on one side of the body, loss of balance, headache, blurred vision, difficulty speaking
  • Serious infections: fever, headache, chills, body aches, cough, weakness
  • Suicidal thoughts or behaviors
  • Seizures
  • Difficulty swallowing
When do Latuda (lurasidone) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Sleepiness
Difficulty controlling movement
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Absence of or decrease in body movement

difficulty with swallowing

drooling

inability to sit still

incremental or ratchet-like movement of the muscle

loss of balance control

mask-like face

muscle discomfort

muscle trembling, jerking, or stiffness

need to keep moving

restlessness

rigid or stiff muscles

shakiness in the legs, arms, hands, or feet

shuffling walk

slow movements

slow reflexes

slurred speech

stiffness of the arms and legs

tic-like (jerky) movements of the head, face, mouth, and neck

trembling or shaking of the hands or feet

twisting movements of the body

uncontrolled movements, especially of the face, neck, and back

Less common

Arm, back, or jaw pain

blurred vision

burning while urinating

changes in patterns and rhythms of speech

chest pain or discomfort

chills

cold sweats

confusion

difficult or painful urination

difficulty opening the mouth

difficulty with breathing

dizziness

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse

fixed position of the eye

headache

high fever

inability to move the eyes

inability to speak

increased blinking or spasms of the eyelid

increased sweating

lockjaw

loss of bladder control

muscle spasm, especially of the neck and back

nervousness

pale skin

pounding in the ears

seizures

severe muscle stiffness

severe or sudden headache

slow or fast heartbeat

slurred speech

sticking out of the tongue

sweating

temporary blindness

tiredness

trouble with breathing, speaking, or swallowing

troubled breathing with exertion

uncontrolled twisting movements of the neck, trunk, arms, or legs

unusual bleeding or bruising

unusual facial expressions

unusual tiredness or weakness

unusually pale skin

weakness in the arm or leg on one side of the body, sudden and severe

Rare

Black, tarry stools

bloody urine

breast pain or swelling

cough

dark-colored urine

decreased frequency or amount of urine

fever

increased thirst

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

lower back or side pain

muscle cramp, pain, or stiffness

nausea

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swelling of the face, fingers, or lower legs

swollen glands

vomiting

weight gain

Incidence not known

Decreased urine output

hives or welts, itching, skin rash

loss of consciousness

redness of the skin

swelling of the throat or tongue

tightness in the chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Anxiety

belching

drowsiness

dry mouth

heartburn

hyperventilation

indigestion

irritability

relaxed and calm feeling

sleepiness or unusual drowsiness

stomach discomfort, upset, or pain

trouble sleeping

unusually deep sleep

unusually long duration of sleep

Less common

Abnormal dreams

back pain

blurred vision

burning feeling in the chest or stomach

decreased appetite

diarrhea

feeling of constant movement of self or surroundings

indigestion

sensation of spinning

sweating

tenderness in the stomach area

watering of mouth and drooling

Rare

Decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

unexpected or excess milk flow from the breasts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Latuda (lurasidone)

thumbs-up

Pros

Works well for depression from bipolar disorder and schizophrenia

Only need to take it once a day

Can use in adults and children

Less likely to affect your weight than other antipsychotics

thumbs-down

Cons

Can take several weeks before you feel the full effects

Can make you feel sleepy

Can cause movement problems

Only available as a tablet

pharmacist-tips

Pharmacist tips for Latuda (lurasidone)

pharmacist
  • Let your provider know about all the medications you're taking before you start Latuda (lurasidone). And don't start any new medications without talking to your provider or pharmacist first. Latuda (lurasidone) interacts with a lot of medications, so your provider should make sure all your medications are safe to take together.

    • Take Latuda (lurasidone) once a day at the same time every day. Take the medication with food that has at least 350 calories. This helps your body absorb the medication better so it can work as best as possible for you.

      • Latuda (lurasidone) can make you sleepy and dizzy. Don't drive or operate heavy machinery until you know how the medication affects you.

        • Speak with your provider about your alcohol consumption while you're taking Latuda (lurasidone). It might be best to avoid drinking alcohol because it can worsen your symptoms. In addition, alcohol can worsen sleepiness and dizziness side effects.

          • Latuda (lurasidone) can cause a drop in blood pressure and make you feel dizzy when you're changing positions, such as from sitting to standing. This is more common when you start treatment and when your dose changes. Get up slowly and try to hold onto something for stability. Get medical help right away if you fall or hit your head.

            • Latuda (lurasidone) can make it harder for your body to cool down when your body temperature gets too high. You might be more likely to get dehydrated and overheated. Make sure to drink plenty of water to stay hydrated. Let your provider know if you feel very hot or thirsty, notice a change in the amount of sweat or urine you make, or if you notice very dark-colored urine.

              • Latuda (lurasidone) can raise blood sugar levels for some people. Ask your provider whether you need to check your blood sugar more often during treatment if you have diabetes.

                • During treatment, it's important that you regularly exercise and eat a balanced diet with fruits, vegetables, and low-fat and low-sugar foods. It's possible for Latuda (lurasidone) to raise your cholesterol (fat) levels in your blood and cause changes in weight in some people.

                  • Although rare, Latuda (lurasidone) can cause difficulty swallowing, which can raise the risk for choking. Make sure to take small bites of food and eat slowly to lower your risk for choking.

                    • If you've taken Latuda (lurasidone) for a long time, don't suddenly stop taking it without talking to your provider first. Otherwise, you might have withdrawal symptoms, such as nausea, headache, sweating, sleeping problems, or mood changes (e.g., anxiety, depression). It might also cause an imbalance of chemicals in your brain that can make your mood symptoms come back. Work with your provider to lower your dose gradually to safely stop Latuda (lurasidone) and prevent withdrawal symptoms from happening.

                      faqs

                      Frequently asked questions about Latuda (lurasidone)

                      Does Latuda (lurasidone) cause weight gain?
                      It's possible to gain weight from Latuda (lurasidone), but the risk appears to be quite low. In clinical studies, people who took this medication reported gaining an average of only 1 pound. A large study on the effects of antipsychotics on weight found that people taking Latuda (lurasidone) had lower risk of noticeable weight gain than other common antipsychotics. In fact, this study actually suggested that people taking Latuda (lurasidone) had a higher chance of noticeable weight loss than other commonly used antipsychotics. Another study also reported that people lost an average of 2 pounds after a year of treatment with Latuda (lurasidone). Make sure to maintain a healthy diet and keep a regular exercise routine while you're taking Latuda (lurasidone). Contact your provider if you're concerned with any weight changes you've had during treatment.
                      Does Latuda (lurasidone) make you sleepy?
                      Yes, sleepiness is one of the most common side effects of Latuda (lurasidone). Across several clinical trials, up to 17% of adults and children who took this medication reported sleepiness as a side effect. But keep in mind that some people can also have other sleep problems like trouble sleeping while they're taking Latuda (lurasidone). When you first start Latuda (lurasidone), see if and how the medication affects your sleep. Contact your provider if it's making you too sleepy or interrupting your sleep. Your provider can try to ease the side effect by making changes to your dose or the timing of when you take it.
                      Can you cut Latuda (lurasidone) in half?
                      The manufacturer doesn't specify whether the Latuda (lurasidone) tablets can be cut in half. Splitting the tablets in half might not be safe and might affect how well the medication works. Speak with your provider if you have trouble swallowing Latuda (lurasidone) tablets whole. There might be other medications available for you with formulations that might be easier to take.
                      How long does it take Latuda (lurasidone) to work for bipolar depression?
                      It can take up to 6 weeks for Latuda (lurasidone) to work to help with depression from bipolar disorder, but a study showed that the medication's effects can start as early as within 2 weeks of treatment. Keep in mind that each person responds to Latuda (lurasidone) differently. Contact your provider if you're not sure whether Latuda (lurasidone) is working for you. But don't stop taking the medication suddenly because you might get withdrawal symptoms, such as trouble sleeping, nausea, or vomiting. Discuss with your provider about your treatment before you make any changes so your provider can make sure you do so safely.
                      How long does Latuda (lurasidone) stay in your system?
                      It can take about 4 days for most of Latuda (lurasidone) to leave the body. Keep in mind that how long the medication stays in your system can depend on your age and your kidney or liver function. This general time frame is estimated based on the half-life of the medication. It’s possible that some side effects can last as long as this time frame.
                      Does Latuda (lurasidone) help anxiety?
                      Latuda (lurasidone) isn't FDA-approved for anxiety. But there's some research showing that Latuda (lurasidone) might work to help with anxiety symptoms in people with bipolar disorder and people with major depressive disorder. This is considered an "off-label" use of Latuda (lurasidone). Don't take this medication for anxiety without speaking with your provider first. Your provider can discuss whether Latuda (lurasidone) is right for you.
                      Can you take Latuda (lurasidone) while pregnant?
                      Talk with your provider about the risks and benefits of taking Latuda (lurasidone) if you're pregnant or thinking of getting pregnant. Studies suggest that many atypical antipsychotics don't raise the risk for miscarriage or birth defects. But it might cause pregnancy complications for mothers, such as gestational diabetes. Also, antipsychotics can raise the risk of abnormal muscle movements and withdrawal symptoms in babies at birth if they're taken during the last 3 months of pregnancy. If you're going to take Latuda (lurasidone) during pregnancy, it's recommended that you enroll in the National Pregnancy Registry for Atypical Antipsychotics by visiting their website or by calling 1-866-961-2388. This registry helps researchers learn more about how safe Latuda (lurasidone) is for you and your baby when it's taken during pregnancy.
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                      warings-icon

                      What are the risks and warnings for Latuda (lurasidone)?

                      Latuda (lurasidone) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                      risk-warning

                      Worsening depression, suicidal thoughts, and unusual behavior

                      • Risk factors: Age under 24 years old | History of depression or other mental health conditions

                        Taking Latuda (lurasidone) can make your depression worse and cause you to have thoughts of suicide or harming yourself. The risk is highest if you're 24 years of age or younger, during the first few months of taking the medication, and when your dose changes. Get medical help right away if you or anyone around you notices that you have suicidal thoughts or unusual behavior (e.g., anxiety, panic attacks, difficulty sleeping, feeling angry or irritated, restlessness) while you're taking Latuda (lurasidone).

                        risk-warning

                        Higher risk of death in older adults with dementia-related psychosis

                        People over the age of 65 who also have dementia sometimes have some of the symptoms of schizophrenia, like hallucinations and delusions. This is called dementia-related psychosis, and it should not be treated with Latuda (lurasidone). Clinical studies found that more strokes and deaths happened in older adults with dementia-related psychosis who were treated with this medication. In studies, the causes of death were often linked to stroke, heart problems, other blood vessel problems, or infection. Let your provider know if you or your loved one has dementia before starting Latuda (lurasidone).

                        risk-warning

                        Neuroleptic malignant syndrome

                        Taking antipsychotic medications like Latuda (lurasidone) can cause a rare, but life-threatening condition called neuroleptic malignant syndrome. Symptoms include fever, sweating, stiff muscles, confusion, not being aware of your surroundings, and fast or irregular heartbeat. Get medical attention as soon as possible if you have any of these symptoms while you're taking Latuda (lurasidone). You might need to stop taking Latuda (lurasidone) and switch to a different medication.

                        risk-warning

                        Difficulty controlling muscle movements (tardive dyskinesia)

                        • Risk factors: Older adults | Women who are 65 years or older | Higher than recommended doses of Latuda (lurasidone) | Taking Latuda (lurasidone) for a long time

                          Latuda (lurasidone) can cause uncontrolled muscle movements in the tongue, face, mouth, lips, neck, hands, arms, legs, and feet (called tardive dyskinesia). The risk for these movement problems and for them to be permanent goes up the longer you take the medication and the higher your dose. Your provider will prescribe the lowest dose possible for the shortest period of time for your symptoms to lower your risk of tardive dyskinesia. Stop taking Latuda (lurasidone) and talk to your provider right away if you notice any unusual movements that you can't control.

                          risk-warning

                          Changes in weight, blood sugar levels, and cholesterol levels

                          • Risk factors: Diabetes | High cholesterol | Considered obese

                            Medications like Latuda (lurasidone) can cause changes in your blood sugar and cholesterol levels. It can also cause changes in your appetite or weight. Your provider might order blood tests regularly throughout treatment to make sure your blood sugar and cholesterol levels are in a healthy range. Make sure to follow a healthy and balanced diet that's low in fat and sugar and keep a regular exercise routine while you're taking Latuda (lurasidone).

                            risk-warning

                            High prolactin levels

                            Latuda (lurasidone) can cause prolactin hormone levels in your blood to go up. High prolactin levels can lead to symptoms such as milky discharge from the nipple, enlarged breasts, and absent or irregular menstrual periods. Talk to your provider if you experience or have any concerns about these symptoms.

                            risk-warning

                            Changes in blood pressure and risk of falls

                            • Risk factors: Low blood pressure | Taking medications that lower blood pressure | History of medical conditions that can lower blood pressure | High Latuda (lurasidone) doses | Liver or kidney problems | 65 years or older

                              Latuda (lurasidone) can make you tired, lower your blood pressure when you stand up, or cause you to lose your balance. This can lead to falls and accidental injuries. Make sure to get up slowly and hold onto something when you stand from a sitting or lying position. Contact your provider if you experience a fall while you're taking Latuda (lurasidone).

                              risk-warning

                              Risk of infection (from low white blood cell count)

                              • Risk factors: Poor immune system

                                Though rare, Latuda (lurasidone) can lower your white blood cell counts (WBCs) and put you at risk for infections. You might need to get blood tests done regularly during the first few months of treatment so your provider can make sure your WBCs are in a safe range. If your WBC count drops too low, you'll probably need to stop taking Latuda (lurasidone). Contact your provider right away if you have any signs of infection that don't go away, such as fever, tiredness, chills, cough, or trouble breathing.

                                risk-warning

                                Difficulty concentrating and extreme sleepiness

                                • Risk factors: Taking high doses of Latuda (lurasidone) | Age 65 years or older | Drinking alcohol | Taking other medications that can cause sleepiness

                                  Latuda (lurasidone) can cause extreme sleepiness and lower your ability to think, react, and focus. Your risk is higher if you're also taking other medications that can cause drowsiness, such as benzodiazepines, anxiety medications, muscle relaxants, and sleep medications. Make sure you know how Latuda (lurasidone) affects you before driving a car or doing activities that require your concentration. Talk to your healthcare provider right away if you feel too sleepy from Latuda (lurasidone).

                                  risk-warning

                                  Seizures

                                  • Risk factors: History of seizures | Health conditions that make it easier to get seizures

                                    Latuda (lurasidone) can potentially raise your risk of having seizures. Before starting this medication, let your provider know if you have a history of seizures or have a medical condition that puts you at risk for getting seizures.

                                    risk-warning

                                    Triggering a manic episode

                                    Though rare, taking Latuda (lurasidone) for depression from bipolar disorder can trigger a bipolar manic episode. Talk to your provider right away if you or your loved ones notice unusual changes in your behavior, such as racing thoughts, restlessness, getting easily distracted, or unusual talkativeness.

                                    risk-warning

                                    Side effects affecting the nervous system in people with Parkinson's disease or Lewy body dementia

                                    People with Parkinson's disease and Lewy body dementia are potentially more sensitive to medications like Latuda (lurasidone). Some signs of higher sensitivity include confusion, unstable posture, falls, movement problems, and similar symptoms of neuroleptic malignant syndrome. It's important to get medical help right away if you or your loved ones notice these effects so you can be examined by a provider.

                                    dosage

                                    Latuda (lurasidone) dosage forms

                                    The average cost for 30 tablets of 40mg of Latuda (lurasidone) is $1378.57 with a free GoodRx coupon. This is 18.09% off the average retail price of $1683.09.
                                    tablet
                                    Tablet
                                    DosageQuantityPrice as low asPrice per unit
                                    20mg30 tablets$1373.84$45.79
                                    40mg30 tablets$1378.57$45.95
                                    60mg30 tablets$1373.66$45.79
                                    80mg30 tablets$1373.34$45.78
                                    120mg30 tablets$2045.18$68.17

                                    Typical dosing for Latuda (lurasidone)

                                    Your provider will determine your dose of Latuda (lurasidone) based on your condition, whether you have kidney or liver problems, and whether you're taking a medication that interacts with Latuda (lurasidone).

                                    If needed, your provider will adjust your dose over time depending on how well the medication works for you and whether you're having side effects.

                                    Schizophrenia

                                    • Ages 18 years and older: The typical starting dose is 40 mg by mouth once per day. The maximum dose is 160 mg per day.

                                    • Ages 13 to 17 years of age: The typical starting dose is 40 mg by mouth once per day. The maximum dose is 80 mg per day.

                                    Depression from bipolar disorder

                                    • Ages 18 years and older: The typical starting dose is 20 mg by mouth once per day. The maximum dose is 120 mg per day.

                                    • Ages 10 to 17 years of age: The typical starting dose is 20 mg by mouth once per day. The maximum dose is 80 mg per day.

                                    More on Latuda (lurasidone) dosage forms

                                    interactions

                                    Interactions between Latuda (lurasidone) and other drugs

                                    Latuda (lurasidone) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Latuda (lurasidone). Please note that only the generic name of each medication is listed below.

                                    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                                    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                    drug-cost

                                    How much does Latuda (lurasidone) cost?

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                                    contraindications-icon

                                    Latuda (lurasidone) contraindications

                                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Latuda (lurasidone) will not be safe for you to take.
                                    alternatives

                                    What are alternatives to Latuda (lurasidone)?

                                    There are a number of medications that your doctor can prescribe in place of Latuda (lurasidone). Compare a few possible alternatives below.
                                    Latuda (lurasidone)
                                    Used for:
                                    $1040.08 Lowest GoodRx priceView Prices
                                    Used for:
                                    $13.25 Lowest GoodRx priceView Prices
                                    latest news

                                    What is the latest news about Latuda (lurasidone)?

                                    images

                                    Latuda (lurasidone) images

                                    White Round 65 - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "65".White Round 65 - Lurasidone Hydrochloride 40mg Tablet
                                    White Round 2 And L - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "L" And "2".White Round 2 And L - Lurasidone Hydrochloride 40mg Tablet
                                    White Round F4 - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "F4".White Round F4 - Lurasidone Hydrochloride 40mg Tablet
                                    White Round 684 - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "684".White Round 684 - Lurasidone Hydrochloride 40mg Tablet
                                    White Round 516 And L - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "L" And "516".White Round 516 And L - Lurasidone Hydrochloride 40mg Tablet
                                    White Round 40 And L - Lurasidone Hydrochloride 40mg Tablet
                                    This medicine is White, Round Tablet Imprinted With "L" And "40".White Round 40 And L - Lurasidone Hydrochloride 40mg Tablet

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                                    References

                                    Best studies we found

                                    California State Board of Pharmacy. (2015). Splitting pills: Understanding the benefits and the risks.

                                    Chapel, S., et al. (2016). Lurasidone dose response in bipolar depression: A population dose-response analysis. Clinical Therapeutics.

                                    Goldberg, J. F., et al. (2023). The effect of lurasidone on anxiety symptoms in patients with bipolar depression: A post hoc analysis. The Journal of Clinical Psychiatry.

                                    View All References (7)
                                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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