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Toviaz

fesoterodine
Used for Overactive Bladder
Used for Overactive Bladder

Fesoterodine fumarate (Toviaz) is an anticholinergic urinary antispasmodic. It relieves symptoms of overactive bladder (OAB) in adults. Brand name Toviaz is also approved to treat neurogenic detrusor overactivity (NDO) in children. Fesoterodine (Toviaz) is an extended-release tablet that's taken by mouth once a day. Some side effects of this medication include dry mouth and constipation.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on January 15, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
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What is Fesoterodine (Toviaz)?

What is Fesoterodine (Toviaz) used for?

How Fesoterodine (Toviaz) works

Fesoterodine (Toviaz) is an anticholinergic medication that blocks acetylcholine. This is a chemical in the body that affects different bodily functions, including telling the bladder muscles to tighten so you can urinate. By blocking acetylcholine, fesoterodine (Toviaz) relaxes the bladder muscles so you have better control over urination.

Drug Facts

Common BrandsToviaz
Drug ClassUrinary antispasmodic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$421.10(save 52.48%)
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What are the side effects of Fesoterodine (Toviaz)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults (OAB)Children (NDO)
  • Diarrhea (7-12%)
  • Urinary tract infection (2-10%)
  • Dry mouth (7-10%)
  • Constipation (7%)

Other Side Effects

Adults (OAB)
  • Indigestion
  • Nausea
  • Painful urination
  • Cough
  • Back pain
  • Swelling (edema)
  • Insomnia
Children (NDO)
  • Weight gain
  • Headache

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Angioedema (severe swelling): swelling of the face, arms or legs, lips, tongue, or throat

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Difficulty having a bowel movement

dry mouth

Less common

Bladder pain

bloating or swelling of the face, arms, hands, lower legs, or feet

bloody or cloudy urine

body aches or pain

burning feeling while urinating

chills

cough

decrease in frequency of urination

decrease in urine volume

difficult or painful urination

difficulty in breathing

difficulty in passing urine (dribbling)

dry eyes

ear congestion

fever

frequent urge to urinate

headache

loss of voice

lower back or side pain

nasal congestion

rapid weight gain

runny nose

sneezing

sore throat

tingling of the hands or feet

unusual tiredness or weakness

unusual weight gain or loss

Incidence not known

Blurred vision

fast, irregular, pounding, or racing heartbeat or pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Back pain

belching

dry throat

heartburn

indigestion

nausea

rash

stomach discomfort, upset, or pain

trouble sleeping

upper abdominal pain

Incidence not known

Dizziness

itching skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Fesoterodine (Toviaz)

thumbs-up

Pros

Taken by mouth

Taken once a day

Available as a lower-cost generic

thumbs-down

Cons

Interacts with many medications

Can cause dry mouth and constipation

Can't be used by people with an allergy to tolterodine (Detrol)

pharmacist-tips

Pharmacist tips for Fesoterodine (Toviaz)

pharmacist

  • You can take fesoterodine (Toviaz) with or without food. Swallow the capsules whole and take them with a liquid. Don't break, crush, or chew them.

    • Fesoterodine (Toviaz) can cause drowsiness, dizziness, and blurry vision. Drinking alcohol can worsen these side effects. Don't drive or do anything that requires you to focus until you know how this medication affects you.

      • Be careful in hot weather. Fesoterodine (Toviaz) can make you sweat less. This can lead to heat exhaustion because sweating helps your body cool down.

        • If you forget to take your dose of fesoterodine (Toviaz), just skip it and take your next scheduled dose. Never take two tablets in the same day because this can cause dangerous side effects.

          • Fesoterodine (Toviaz) interacts with many medications. These include anticholinergics, ketoconazole, clarithromycin, and more. Your provider might need to adjust your doses, so make sure to tell them all of the medications you're taking.

            faqs

            Frequently asked questions about Fesoterodine (Toviaz)

            Can I just stop taking fesoterodine (Toviaz)?
            Before stopping fesoterodine (Toviaz), it's best to speak to your healthcare provider first. Fesoterodine (Toviaz) helps relax your bladder muscles while you're taking it, but it doesn't cure overactive bladder. If you stop taking the medication, your OAB symptoms might return. It's important to know that if you experience a serious allergic reaction to this medication, you should stop taking it and get emergency help right away.
            Can fesoterodine (Toviaz) be cut in half?
            No, you shouldn't chew, cut, or crush fesoterodine (Toviaz). This is because the tablets are extended-release, meaning they release the medication slowly in your body over time. If you cut the tablet, you could change the way the medication is released in your body; this could lead to side effects. If you have trouble swallowing fesoterodine (Toviaz), talk to your provider about other treatment options that might be easier for you to take.
            Can fesoterodine (Toviaz) cause urinary retention?
            Though rare, fesoterodine (Toviaz) can cause urinary retention (when your bladder holds on to too much urine). Clinical studies show only about 1% of people experienced this as a side effect. But please note that you can't take fesoterodine (Toviaz) if you already have urinary retention or any blockage in the urinary tract. Doing so can lead to kidney injury and other complications. Talk with your provider if you're not sure whether fesoterodine (Toviaz) is a good choice for you.
            Does fesoterodine (Toviaz) cause constipation?
            Constipation is a common side effect of fesoterodine (Toviaz). Some things you can do to prevent constipation include eating foods that are high in fiber, drinking plenty of water, and exercising regularly. You can also ask your provider about a fiber supplement. If it becomes too bothersome, they might be able to adjust your dose or recommend a different treatment option.
            Can you take fesoterodine (Toviaz) and Myrbetriq together?
            If you've tried taking either fesoterodine (Toviaz) or Myrbetriq (mirabegron) alone and they haven't worked well for you, your provider might consider having you take both medications together. The two medications work in different ways to treat OAB symptoms, so you might see a benefit from taking both together.
            Does fesoterodine (Toviaz) have a generic?
            Yes, fesoterodine (Toviaz) comes in a generic version.
            How long does it take fesoterodine (Toviaz) to start working?
            In one study, people taking for OAB symptoms saw improvement in their symptoms after 1 week of treatment. Keep in mind that it can take up to 8 weeks or longer to see more noticeable results. It's important that you continue to take fesoterodine (Toviaz) every day, even if you don't see results right away.
            What is the best time of day to take fesoterodine (Toviaz)?
            Fesoterodine (Toviaz) can be taken at any time of the day. It's most important to take it at the same time every day so the amount of medication in your body stays consistent. If you feel sleepy after taking fesoterodine (Toviaz), try taking it at night before you go to bed.
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            What are the risks and warnings for Fesoterodine (Toviaz)?

            Fesoterodine (Toviaz) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Unusual swelling of the face, lips, or throat (angioedema)

            Fesoterodine (Toviaz) can cause swelling of the face, lips, tongue, or throat due to an allergic reaction. This can make it hard to breathe and it can happen after taking the first dose or after taking multiple doses. If you experience these symptoms, stop taking the medication and get emergency medical help right away.

            risk-warning

            Trouble urinating and stomach problems

            • Risk factors: History of bladder problems | History of stomach or intestine problems | Severe constipation

              People who have a blockage in the bladder shouldn't take fesoterodine (Toviaz). This medication can make it difficult for you to empty your bladder fully, which can lead to kidney injury and other complications. In addition, don't take fesoterodine (Toviaz) if you have blockages in your stomach or intestines. Fesoterodine (Toviaz) can slow down your digestion, which can make your stomach symptoms worse.

              risk-warning

              Vision changes

              • Risk factors: History of narrow-angle glaucoma

                Fesoterodine (Toviaz) can cause changes to your vision. This is more likely to happen if you have glaucoma. Fesoterodine (Toviaz) isn't recommended if you have a condition called uncontrolled narrow-angle glaucoma. Check with your provider if you're unsure what type of glaucoma you have.

                risk-warning

                Dizziness and drowsiness

                • Risk factors: Drinking alcohol | Taking other medications that make you less alert | Age 65 years or older

                  Fesoterodine (Toviaz) can make you feel dizzy, drowsy, or less alert, particularly when you first start the medication or raise your dose. Don't drive or do things that require you to focus until you know how this medication affects you.

                  risk-warning

                  Myasthenia gravis

                  If you have myasthenia gravis, a condition which causes your muscles to feel weak, talk to your provider before taking fesoterodine (Toviaz) because it can worsen your symptoms.

                  dosage

                  Fesoterodine (Toviaz) dosage forms

                  The average cost for 30 tablets of 8mg of Fesoterodine (Toviaz) is $200.10 with a free GoodRx coupon. This is 52.48% off the average retail price of $421.10.
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  4mg30 tablets$200.10$6.67
                  8mg30 tablets$200.10$6.67

                  Typical dosing for Fesoterodine (Toviaz)

                  • Overactive bladder (adults): The typical starting dose is 4 mg by mouth once a day. Your provider might raise your dose to 8 mg once a day depending on how you respond to the medication.

                  • Neurogenic detrusor overactivity (children ages 6 years and older, weighing at least 25 kg): The typical dose is 4 mg by mouth once a day. If needed, your child's provider might raise their dose to 8 mg once a day depending on how your child responds to the medication.

                  Your dose might differ if you have kidney problems or if you're taking certain medications that interact with fesoterodine (Toviaz).

                  interactions

                  Interactions between Fesoterodine (Toviaz) and other drugs

                  Fesoterodine (Toviaz) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Fesoterodine (Toviaz). Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  • Potassium

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  How much does Fesoterodine (Toviaz) cost?

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                  Toviaz (brand)
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                  contraindications-icon

                  Fesoterodine (Toviaz) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Fesoterodine (Toviaz) will not be safe for you to take.
                  alternatives

                  What are alternatives to Fesoterodine (Toviaz)?

                  There are a number of medications that your doctor can prescribe in place of Fesoterodine (Toviaz). Compare a few possible alternatives below.
                  Fesoterodine (Toviaz)
                  Used for:
                  $200.10 Lowest GoodRx priceView Prices
                  Oxybutynin
                  Used for:

                  • Overactive bladder

                  • Incontinence in children due to a neurologic (brain) condition, such as spina bifida

                  $8.50 Lowest GoodRx priceView Prices
                  Tolterodine (Detrol)
                  Used for:

                  • Overactive bladder (OAB)

                  $26.75 Lowest GoodRx priceView Prices
                  images

                  Fesoterodine (Toviaz) images

                  Blue Oval Ft - Toviaz 8mg Extended-Release Tablet
                  This medicine is Blue, Oval Tablet Imprinted With "Ft".Blue Oval Ft - Toviaz 8mg Extended-Release Tablet

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                  References

                  Best studies we found

                  AvKARE. (2021). Fesoterodine fumarate- fesoterodine fumarate tablet, extended release [package insert]. DailyMed.

                  Cameron, A. P., et al. (2024). The AUA/SUFU Guideline on the diagnosis and treatment of idiopathic overactive bladder (2024). Journal of Urology.

                  Goldman, H. B., et al. (2011). Early onset of fesoterodine efficacy in subjects with overactive bladder. British Journal of Urology International.

                  View All References (2)

                  Haab, F. (2014). Chapter 1: The conditions of neurogenic detrusor overactivity and overactive bladder. Neurourology and Urodynamics.

                  Pfizer Laboratories Div Pfizer Inc. (2024). Toviaz- fesoterodine fumarate tablet, film coated, extended release [package insert]. DailyMed.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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