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Xeomin vs. Botox

Xeomin (incobotulinumtoxinA) is an injectable medication used to treat many movement problems, drooling, and frown lines, but it can have dangerous side effects if it spreads to areas outside of the injection. It's typically administered by a healthcare provider.

• Long-term excessive drooling (sialorrhea) in people 2 years and older
• Arm spasms in people 2 years and older
• Uncontrollable neck spasms (cervical dystonia) in adults
• Uncontrollable eye twitching (blepharospasm) in adults
• Frown lines in adults

Excessive drooling:

• Need for tooth removal (5% in adults)
• Dry mouth (4% in adults)
• Diarrhea (4% in adults)
• High blood pressure (4% in adults)
• Fall (3% in adults)
• Bronchitis (3% in adults, 1% in children)
• Trouble speaking (3% in adults)
• Back pain (3% in adults)
• Dry eye (3% in adults)

Arm spasms:

• Seizure (3% in adults)
• Nose and throat infection (2% in adults, 3-6% in children)
• Bronchitis (2-3% in children)

Neck spasms:

• Trouble swallowing (13-18%)
• Nervous system problems (16-17%)
• Neck pain (7-15%)
• Infections (13-14%)
• Breathing problems (10-13%)
• Muscle weakness (7-11%)
• Pain at injection site (4-9%)
• Muscle or bone pain (4-7%)

Eye twitching:

• Drooping eyelid (19%)
• Dry eye (16%)
• Dry mouth (16%)
• Vision changes (e.g., blurred vision, 12%)
• Injection site reaction (11%)
• Diarrhea (8%)
• Headache (7%)
• Nose and throat infection (5%)
• Respiratory tract infection (5%)
• Shortness of breath (5%)

Frown lines:

• Headache (5%)

• Spread of toxin effects
• Difficulty swallowing or breathing
• Eye problems due to reduced blinking
• Worsening of glaucoma
• Drooping eyelids

Botox (onabotulinumtoxinA) is a prescription injection used for many medical conditions caused by muscle overactivity or nerve problems. It's FDA approved for treating conditions like overactive bladder, excessive armpit sweating, and for preventing migraines. The medication is injected by a trained healthcare professional. Side effects depend on where the injection is given, but they can include urinary tract infections, headache, and neck pain.

Botox (onabotulinumtoxinA) is different from Botox Cosmetic, which is used for facial and neck lines.

• Overactive bladder (OAB) - adults
• Loss of bladder control caused by nerve-bladder problems - adults
• Nerve-related bladder problem - children 5 years and older
• Headache prevention for chronic migraine - adults
• Muscle spasms - adults and children 2 years and older
• Neck muscle spasms - adults
• Excessive armpit sweating - adults
• Eyelid twitching - adults and children 12 years and older
• Crossed eyes - adults and children 12 years and older

Overactive bladder:

• Urinary tract infection (18%)
• Painful urination (9%)
• Trouble emptying the bladder (6%)

Loss of bladder control:

• Urinary tract infection (24-26%)
• Urine left in the bladder (17%)
• Trouble emptying the bladder (15-17%)
• Difficulty passing urine (15%)

Chronic migraine:

• Neck pain (9%)
• Headache (5%)

Muscle spasms:

• Pain in the arm or leg (up to 9%)
• Muscle weakness (up to 4%)

Neck muscle spasm:

• Trouble swallowing (19%)
• Upper respiratory infection (12%)
• Neck pain (11%)
• Headache (11%)

Excessive armpit sweating:

• Injection site pain (3-10%)
• Bleeding (3-10%)
• Infection (3-10%)

Eyelid twitching:

• Droopy eyelid (21%)
• Damage to surface of the eye (6%)
• Dry eye (6%)

Crossed eyes:

• Droopy eyelid (1-38%)
• Eye misalignment (17%)

• Spread of toxin effect
• Serious allergic reaction
• Difficulty swallowing or breathing
• Lung problems in people with breathing conditions
• Eye problems and bleeding
• Bronchitis and upper respiratory tract infections
• Overactive nervous system
• Urinary tract infections
• Trouble emptying the bladder
• Transmission of diseases