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Clindamycin vs. Tretinoin

Clindamycin (Cleocin) is a lincosamide antibiotic that's used to treat many different serious bacterial infections, such as strep throat and skin infections. This antibiotic is approved for use in both adults and children. Clindamycin (Cleocin) is available as a capsule and liquid that are taken 3 or 4 times per day, depending on your age and your infection. It's also available as an injection that's given by a healthcare professional. Side effects include stomach upset, itching, and rash.

• Skin infections (e.g., cellulitis)
• Lower respiratory tract infections (e.g., pneumonia, bronchitis)
• Stomach infections
• Pelvic and genital tract infections
• Bloodstream infections
• Bone and joint infections - injection form only

• Diarrhea
• Nausea
• Vomiting
• Stomach pain
• Skin rash
• Itching

• Severe allergic reactions and skin reactions
• Diarrhea from Clostridioides difficile infection
• Development of drug-resistant bacteria

Retin-A (tretinoin) is a retinoid medication that's used to treat acne in adults and children 12 years and older. It's available as a cream or a gel that's applied onto the skin once a day. Side effects include skin irritation, redness, and peeling. Your acne might get worse at the beginning of treatment, but it should get better as you continue using the medication. You must have a prescription for Retin-A (tretinoin) from your primary care provider or dermatologist; this medication isn't available over the counter.

• Acne

• Skin peeling or discomfort
• Warm feeling or stinging after applying
• Skin redness
• Sensitivity to sunlight (sunburns)
• Worsening of acne in the first few weeks of treatment

• Sunburns
• Skin irritation in extreme weather
• Skin reactions