Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Tretinoin, available as Altreno (topical) and tretinoin oral capsules, is a retinoid medication used to treat different conditions. Both forms are derived from vitamin A and are used for their ability to promote cell turnover. Altreno (tretinoin) is a topical lotion used to treat acne in people 9 years and older, while tretinoin oral capsules are used to treat acute promyelocytic leukemia (APL), a type of blood cancer. Altreno is applied once daily to the skin, whereas tretinoin oral capsules are taken by mouth twice daily. Altreno is available by prescription only and is not available as a generic, while tretinoin oral capsules are available in generic form. Common side effects of Altreno include dryness, pain, and redness at the application site, while tretinoin oral capsules can cause severe headaches, dizziness, and a risk of blood clots. Additionally, tretinoin oral capsules have serious risks such as differentiation syndrome and birth defects if taken during pregnancy, requiring the use of two forms of birth control during treatment.
Altreno (tretinoin)
Retin-a (tretinoin)
Altreno (tretinoin)
Retin-a (tretinoin)
Summary of Altreno vs. Tretinoin
Summary for Retinoid
Prescription only
Altreno (tretinoin) is a retinoid medication that's used to treat acne in people 9 years and older. Altreno (tretinoin) is a lotion that you apply once daily to the affected area(s) on your skin. It isn't sold over the counter and requires a prescription. Some side effects of Altreno (tretinoin) include dryness, pain, and redness where you apply the medication.
Summary for Retinoid
Prescription only
Retin-A (tretinoin) is a retinoid medication that's used to treat acne in adults and children 12 years and older. It's available as a cream or a gel that's applied onto the skin once a day. Side effects include skin irritation, redness, and peeling. Your acne might get worse at the beginning of treatment, but it should get better as you continue using the medication. You must have a prescription for Retin-A (tretinoin) from your primary care provider or dermatologist; this medication isn't available over the counter.
Indications of Altreno vs. Tretinoin
Indications for
•Acne
Indications for
•Acne
Pros and Cons of Altreno vs. Tretinoin
Pros and Const for Retinoid
Pros
•Applied once daily
•Applied directly on the affected area(s)
•Can use for acne in children as young as 9 years old
Cons
•Can take many weeks before you notice improvement in your skin