Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Azelaic acid (Finacea) and tretinoin (Retin-A) are both prescription medications, but they treat different conditions. Azelaic acid (Finacea) is a dicarboxylic acid used topically to treat mild-to-moderate rosacea, while tretinoin (Retin-A) is an topical medication used to treat acne in adults and children 12 years and older. Azelaic acid is applied to the skin as a gel or foam twice daily, while tretinoin (Retin-A) is available as a cream or a gel applied to the skin once daily. Both medications are available as a lower-cost generic. Common side effects of azelaic acid include mild burning and itching, while tretinoin can cause skin irritation, redness, and peeling. Azelaic acid is generally considered safe during pregnancy, but tretinoin isn't typically recommended for use during pregnancy. Tretinoin may cause your acne to get worse at the beginning of treatment, but it should get better as you continue using the medication.
Azelaic acid (Finacea)
Retin-a (tretinoin)
Azelaic acid (Finacea)
Retin-a (tretinoin)
Summary of Finacea vs. Tretinoin
Summary for Dicarboxylic acid
Prescription only
Azelaic acid (Finacea) is a dicarboxylic acid. It's a topical medication used to treat mild-to-moderate rosacea in adults. It works by easing skin redness and inflammation. Azelaic acid (Finacea) is applied to the skin twice daily, in the morning and evening. This medication comes as a gel and foam. Some side effects of azelaic acid (Finacea) include mild burning, tingling, and itching. It's available as brand name and generic medications.
Summary for Retinoid
Prescription only
Retin-A (tretinoin) is a retinoid medication that's used to treat acne in adults and children 12 years and older. It's available as a cream or a gel that's applied onto the skin once a day. Side effects include skin irritation, redness, and peeling. Your acne might get worse at the beginning of treatment, but it should get better as you continue using the medication. You must have a prescription for Retin-A (tretinoin) from your primary care provider or dermatologist; this medication isn't available over the counter.
Indications of Finacea vs. Tretinoin
Indications for
•Treatment of papules and pustules in adults with mild-to-moderate rosacea
Indications for
•Acne
Pros and Cons of Finacea vs. Tretinoin
Pros and Const for Dicarboxylic acid
Pros
•Available as a gel and foam
•Applied to the skin; convenient for people who don't like pills
•Can wear cosmetics after it dries
Cons
•Might take months to see improvement
•Can cause skin irritation, such as burning or dryness