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Terbinafine vs. Tinactin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Terbinafine (brand name: Lamisil) and Tinactin (generic name: tolnaftate) are both antifungal medications, but they have some key differences. Terbinafine oral tablet is a prescription-only medication primarily used to treat fungal infections of the toenails and fingernails, while Tinactin is an over-the-counter topical treatment for skin fungal infections like athlete's foot, ringworm, and jock itch. Terbinafine works by preventing the fungus from forming its protective outer layer, whereas Tinactin blocks a protein that fungi need to grow. Terbinafine is taken once daily and can take several weeks to show results, with potential side effects including headache, rash, and liver damage. On the other hand, Tinactin is applied to the skin twice daily and typically causes only mild skin irritation. Tinactin is available in various forms such as sprays, creams, and powders. Oral terbinafine requires a prescription but is also available over-the-counter in topical forms.

Terbinafine

 

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Tolnaftate

 

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Summary for Terbinafine

Prescription only

Terbinafine is used to treat fingernail and toenail fungus in adults. It's a type of antifungal that helps get rid of the fungus. Terbinafine is a tablet you take once a day, but treatment can take many weeks to finish. Common side effects include headache, rash, and diarrhea. Terbinafine can interact with other medications, including certain antidepressants and beta blockers.

Indications for Terbinafine

Pros and Cons for Terbinafine

Pros

  • Works better to treat nail fungus than other treatment options
  • First-choice over other antifungals that are taken by mouth
  • Taken once a day, with or without food

Cons

  • Can take several weeks to work
  • Can cause loss of taste or smell (sometimes permanently)
  • Not recommended if you have liver problems

Common Side Effects for Terbinafine

  • Headache (13%)
  • Rash (6%)
  • Diarrhea (6%)
  • Indigestion (4%)

Warnings for Terbinafine

  • Liver damage
  • Changes to taste or smell
  • Symptoms of depression
  • Low white blood cell counts
  • Serious skin reactions
  • Lupus flare up
  • Clotting and bleeding problems

Summary for Tinactin

Over-the-counter

Tolnaftate is an over-the-counter (OTC) antifungal medication that's applied to the skin to treat ringworm, jock itch, and athlete's foot. It also helps relieve symptoms like itching, burning, cracking, and redness from these fungal infections. This medication comes in different topical forms, including a spray, powder spray, cream, and liquid. Tolnaftate can be used for adults and children 2 years and older, unless otherwise directed by a provider. Most people have few to no side effects while using this medication, though some can have mild skin irritation.

Indications for Tinactin

Pros and Cons for Tinactin

Pros

  • Available as a generic, over-the-counter medication
  • Available in different topical formulations, such as powder spray, liquid, and cream
  • Typically minor or mild side effects

Cons

  • Can take up to a month to treat athlete's foot or ringworm
  • Only works on some fungal infections; doesn't work on fungal infections of the scalp or nails
  • Can't use on children under 2 years old, unless a provider says it's okay

Common Side Effects for Tinactin

Warnings for Tinactin

  • Use only on your skin
  • Flammable and possible bursting (topical sprays only)

Prices with our coupons for Terbinafine vs. Tinactin

Price Card Drug Icon
Terbinafine30 tablets / 250mg
$14.00$24.71
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Price Card Drug Icon
Tinactin1 bottle / 133g of 1%
$9.18$9.18
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