Key takeaways
Liraglutide (Saxenda) and phentermine (Adipex-P) are both medications used to help with weight loss, but they belong to different medication classes and work in different ways. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that helps control appetite by slowing down your gut, making you feel less hungry. It is injected under the skin once daily. Phentermine, on the other hand, is a sympathomimetic stimulant that suppresses appetite and is taken orally, usually once a day in the morning. While both medications are used for weight management, liraglutide is approved for use in adults and children over 12 with a high body mass index (BMI). Phentermine is only approved for short-term use in people who are 17 years of age and older. Liraglutide is not a controlled substance, but phentermine is a Schedule IV controlled substance due to its potential for misuse and dependence. Common side effects of liraglutide include nausea, vomiting, and diarrhea, while phentermine can cause dry mouth and trouble sleeping. Additionally, you should avoid combining either medication with other weight loss medications.
