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Ketoconazole vs. Oravig

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ketoconazole cream and Oravig (miconazole) are both antifungal medications used to treat fungal infections, but they differ in their specific uses and forms. Ketoconazole cream is applied topically to treat skin infections like ringworm, jock itch, athlete's foot, and seborrheic dermatitis, while Oravig (miconazole) is a buccal tablet used for oral thrush in the mouth and throat. Ketoconazole cream is applied directly to the skin once or twice daily, depending on the condition, and is available as a lower-cost generic. In contrast, Oravig (miconazole) is a prescription-only tablet that dissolves in the mouth over six hours and does not have a generic version. Common side effects of ketoconazole cream include itching and skin irritation, whereas Oravig (miconazole) can cause mouth discomfort, diarrhea, and headaches. Additionally, ketoconazole cream is not known to cause liver damage when used topically, unlike its oral form, while Oravig (miconazole) should be used with caution if you have a milk protein allergy.

ketoconazole cream

 

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Oravig

(miconazole)

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Summary for Ketoconazole

Prescription only

Ketoconazole cream is an antifungal medication. It's used to treat different types of fungal skin infections, including ringworm and yeast skin infections. Ketoconazole cream is approved for adults only. It's typically applied onto the skin once or twice a day. Most people have very few side effects, like itching and stinging where the cream is applied.

Indications for Ketoconazole

Pros and Cons for Ketoconazole

Pros

  • Can treat many different kinds of fungal skin infections
  • Skin usually starts improving shortly after you start using the cream
  • Applied directly to the affected area(s)
  • Has few side effects

Cons

  • Must use for at least 2 weeks (depends on the type of infection)
  • Not available over the counter
  • Some creams have sulfites, which can cause allergic reactions in certain people
  • Not known if safe for people who are pregnant or breastfeeding

Common Side Effects for Ketoconazole

  • Itchiness (5%)
  • Skin irritation (5%)
  • Stinging (5%)

Warnings for Ketoconazole

  • Allergic reaction

Summary for Oravig

Prescription only

Oravig (miconazole) treats fungal infections in the mouth and throat (oral thrush). This medication comes as a tablet that dissolves against your gum in your mouth, so it might be more difficult to use than other medications. The most common side effects of Oravig (miconazole) include upset stomach (e.g., diarrhea, nausea) and headache.

Indications for Oravig

  • Oral thrush of the mouth and throat

Pros and Cons for Oravig

Pros

  • First and only tablet for oral thrush that dissolves against the gum in the mouth
  • Only need to take once daily
  • No serious side effects

Cons

  • Can be tricky to use compared to other medications
  • Can take 6 or more hours to fully dissolve
  • No lower-cost generic available

Common Side Effects for Oravig

  • Mouth discomfort (e.g., pain, swelling; up to 12%)
  • Diarrhea (9%)
  • Headache (8%)
  • Nausea (7%)
  • Vomiting (4%)

Warnings for Oravig

  • Allergic reaction

Prices with our coupons for Ketoconazole vs. Oravig

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Ketoconazole1 tube / 60g of 2%
$19.62$76.62
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Oravig14 buccal tablets / 50mg
$1,253.29$1,562.66
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