Key takeaways
Jardiance (empagliflozin) and Trulicity (dulaglutide) are both medications used to manage Type 2 diabetes, but they work in different ways and have different forms. Jardiance is an oral tablet taken once daily, while Trulicity is an injectable medication used once a week. Jardiance is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that helps your kidneys remove excess sugar through urine, and it also helps with heart failure and chronic kidney disease. On the other hand, Trulicity is a Glucagon-like peptide-1 (GLP-1) agonist that helps your body release more insulin, slows digestion, and reduces sugar release into the bloodstream. Jardiance can cause urinary tract infections and yeast infections, while Trulicity often causes nausea and other stomach issues. Currently, Jardiance does not have a generic version available until at least 2025, whereas Trulicity is only available as a brand-name medication. Both medications can help with weight loss, but neither is specifically approved for this purpose.
