Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Jardiance vs. Wegovy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Jardiance (empagliflozin)
    Wegovy (semaglutide)
  • Jardiance (empagliflozin)
    Wegovy (semaglutide)

  • Summary of Jardiance vs. Wegovy

    Summary for SGLT2 inhibitor
    Prescription only

    Jardiance (empagliflozin) is a brand-name medication that's used along with a nutritious diet and routine exercise to improve blood sugar levels in people 10 years and older with Type 2 diabetes. It can also lower the chance of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Jardiance (empagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's a tablet that's taken by mouth once a day. Side effects can include urinary tract infections (UTIs), yeast infections, and weight loss.

    Summary for GLP-1 agonist
    Prescription only

    Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist that's injected under the skin. It's used together with a lower-calorie diet and regular exercise. Wegovy (semaglutide) is approved to help with weight loss in certain adults and children 12 years of age and older. It also helps lower the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease. The dosing schedule for the injections is once a week. Common side effects include nausea, diarrhea, and stomach pain.

  • Indications of Jardiance vs. Wegovy

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 years and older
    •Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in adults with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for
    •

    Weight loss and long-term weight management in:

    •People ages 12 years and older who are considered obese
    •Adults considered overweight with at least one weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol)
    •

    Lowering the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease

  • Pros and Cons of Jardiance vs. Wegovy

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken by mouth once a day
    •Unlikely to cause weight gain
    •Can take with other diabetes medications
    Cons
    •Raises risk of urinary tract infections (UTIs) and genital yeast infections
    •Might make you urinate more
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for GLP-1 agonist
    Pros
    •Can help you lose weight when it's used along with a nutritious diet and regular exercise
    •Approved for helping with weight loss for children ages 12 years and older considered obese
    •Injected once a week
    Cons
    •Must inject under the skin
    •Can cause stomach pain, nausea, and diarrhea
    •Can't take with other semaglutide products (Ozempic, Rybelsus) or with other GLP-1 agonists

  • Common Side Effects of Jardiance vs. Wegovy

    Common Side Effects for
    •Urinary tract infection (UTI; 8-9%)
    •Vaginal yeast infection in females (5-6%)
    •Upper respiratory tract infection (3-4%)
    •High cholesterol or fat levels (3-4%)
    •Urinating more than usual (3%)
    Common Side Effects for
    •Nausea (44%)
    •Diarrhea (30%)
    •Vomiting (24%)
    •Constipation (24%)
    •Stomach pain (20%)
    •Headache (14%)
    •Tiredness (11%)

  • Warnings of Jardiance vs. Wegovy

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with certain other diabetes medications
    •Leg and foot amputations
    •Allergic reactions
    Common Side Effects for
    •Possible risk for thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Gallbladder problems
    •Low blood sugar
    •Kidney damage
    •Allergic reactions
    •Eye problems in people with Type 2 diabetes (diabetic retinopathy)
    •Faster heart rate
    •Possible risk of self-harm
    •Lung problems during general anesthesia or deep sedation

  • Prices with our coupons for Jardiance vs. Wegovy

    Learn more about Jardiance
    Learn more about Wegovy

Compare other Heart Failure and Weight Loss drugs

Brenzavvy vs JardianceEntresto vs JardianceFarxiga vs JardianceGlucovance vs JardianceGlyxambi vs JardianceInpefa vs JardianceJanuvia vs JardianceJardiance vs ActosJardiance vs AfrezzaJardiance vs GlimepirideJardiance vs GlipizideJardiance vs GlucotrolJardiance vs GlyburideJardiance vs InvokametJardiance vs InvokanaJardiance vs JanumetJardiance vs MetaglipJardiance vs MetforminJardiance vs MounjaroJardiance vs OnglyzaJardiance vs OzempicJardiance vs PrecoseJardiance vs SynjardyJardiance vs TradjentaJardiance vs TrulicityJardiance vs VictozaJardiance vs WegovyRybelsus vs JardianceSteglatro vs JardianceFarxiga vs Glyburide
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.