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Compare Jardiance vs. Synjardy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Jardiance (empagliflozin)
    Synjardy
  • Jardiance (empagliflozin)
    Synjardy

  • Summary of Jardiance vs. Synjardy

    Summary for SGLT2 inhibitor
    Prescription only

    Jardiance (empagliflozin) is a brand-name medication that's used along with a nutritious diet and routine exercise to improve blood sugar levels in people 10 years and older with Type 2 diabetes. It can also lower the chance of serious complications, hospitalization, and death in certain adults with heart failure or chronic kidney disease (CKD). Jardiance (empagliflozin) belongs to the drug class called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It's a tablet that's taken by mouth once a day. Side effects can include urinary tract infections (UTIs), yeast infections, and weight loss.

    Summary for SGLT2 inhibitor / Biguanide
    Prescription only

    Synjardy is a tablet containing empagliflozin (an SGLT2 inhibitor) and metformin (a biguanide). It helps lower blood sugar in people with Type 2 diabetes when used with a balanced diet and regular exercise. Synjardy can also help lower the risk of serious problems in adults with Type 2 diabetes who have heart disease, heart failure, or chronic kidney disease (CKD). Immediate-release tablets (IR) are for people 10 years and older and are taken twice a day. The extended-release tablets (XR) are only for adults and are taken once a day. Side effects include urinary tract infections and genital yeast infections.

  • Indications of Jardiance vs. Synjardy

    Indications for
    •Type 2 diabetes (in addition to diet and exercise) in people age 10 years and older
    •Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in adults with heart failure
    •Lowering the risk of worsening kidney problems, hospitalization, and death due to heart problems in adults with chronic kidney disease (CKD)
    Indications for
    •Type 2 diabetes
    •Lowering the risk of death due to heart problems in adults with Type 2 diabetes and heart disease
    •Lowering the risk of hospitalization and death due to heart problems in adults with Type 2 diabetes and heart failure
    •Lowering the risk of worsening kidney problems, hospitalization, and death due to heart problems in adults with Type 2 diabetes and chronic kidney disease (CKD)

  • Pros and Cons of Jardiance vs. Synjardy

    Pros and Const for SGLT2 inhibitor
    Pros
    •Taken by mouth once a day
    •Unlikely to cause weight gain
    •Can take with other diabetes medications
    Cons
    •Raises risk of urinary tract infections (UTIs) and genital yeast infections
    •Might make you urinate more
    •Not recommended during the second and third trimesters of pregnancy
    Pros and Const for SGLT2 inhibitor / Biguanide
    Pros
    •Combines two medications into one tablet for convenience
    •Not likely to cause weight gain
    •Available in both immediate-release and extended-release versions
    •Immediate-release tablets are okay for children 10 years and older to take
    Cons
    •Need to take with food
    •Might cause urinary tract infections or genital yeast infections
    •Not safe for people with severe kidney problems or on dialysis
    •Not approved for people with Type 1 diabetes

  • Common Side Effects of Jardiance vs. Synjardy

    Common Side Effects for
    •Urinary tract infection (UTI; 8-9%)
    •Vaginal yeast infection in females (5-6%)
    •Upper respiratory tract infection (3-4%)
    •High cholesterol or fat levels (3-4%)
    •Urinating more than usual (3%)
    Common Side Effects for
    •Low blood sugar (up to 16%)
    •Urinary tract infection (up to 9%)
    •Upper respiratory tract infection or common cold (up to 8%)

    Note: Side effect percentages were reported by adults taking empagliflozin, metformin, and a sulfonylurea.

  • Warnings of Jardiance vs. Synjardy

    Common Side Effects for
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure or dehydration)
    •Genital and urinary tract infections
    •Low blood sugar (hypoglycemia) when used with certain other diabetes medications
    •Leg and foot amputations
    •Allergic reactions
    Common Side Effects for
    •Lactic acidosis
    •Ketoacidosis
    •Low fluids in the body (leading to low blood pressure, dehydration, or kidney problems)
    •Genital infections and urinary tract infections
    •Low blood sugar (hypoglycemia) when taken with certain diabetes medications
    •Leg and foot amputations
    •Serious allergic reaction
    •Low vitamin B12 levels

  • Prices with our coupons for Jardiance vs. Synjardy

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    Learn more about Synjardy

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