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Imitrex vs. Relpax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Sumatriptan (Imitrex) and eletriptan (Relpax) are both triptans used to treat migraine attacks with or without aura in adults. Sumatriptan is available in various forms, including tablets, injections, and nasal sprays, while eletriptan is only available as a tablet. Sumatriptan can be taken up to four migraine attacks a month, whereas eletriptan is limited to three migraines a month. Studies suggest that eletriptan might provide longer-lasting relief compared to sumatriptan. Both medications can be taken with over-the-counter pain relievers like acetaminophen or ibuprofen, but you should consult a healthcare professional first. Common side effects for sumatriptan include tingling or numbness, while eletriptan may cause dizziness and sleepiness. Both medications carry risks of serious side effects like heart problems and serotonin syndrome, so it's important to discuss your medical history with your prescriber before starting either medication.

Sumatriptan

(Imitrex)

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Eletriptan

(Relpax)

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Summary for Imitrex

Prescription only

Sumatriptan (Imitrex) is used to treat migraines with or without aura in adults. The medication is typically taken as a single dose for your migraine. But, it's possible that you can take it again 2 hours after the first dose if your migraine doesn't go away. Side effects of sumatriptan (Imitrex) include tingling or numbness of fingers or toes, feeling too warm or too cold, and fatigue. It can interact with antidepressants and other similar migraine medications. Sumatriptan (Imitrex) is available as a lower-cost generic tablet.

Indications for Imitrex

  • Treatment of migraine attacks with or without aura in adults

Pros and Cons for Imitrex

Pros

Cons

  • Can't use to prevent migraines
  • Must wait at least 2 hours after the first dose to take a second dose, if needed
  • Your migraines can get worse if you use this medication too often.
  • Unknown if it's safe or if it works well in children

Common Side Effects for Imitrex

  • Tingling or numbness of fingers or toes (3-5%)
  • Feeling too warm or too cold (2-3%)
  • Fatigue (2-3%)

Warnings for Imitrex

  • Heart problems and high blood pressure
  • Stroke or other brain injury
  • Extreme narrowing of blood vessels
  • Serotonin syndrome
  • Allergic reactions
  • Seizures

Summary for Relpax

Prescription only

Eletriptan, also known by its brand name Relpax, is a triptan that's a first-choice treatment option for adults who have migraine attacks with or without aura. This medication is available as a tablet that's taken by mouth at the first sign of a migraine attack. The dosage can be repeated 2 hours later if the migraine comes back or doesn't go away. Side effects include making you sleepy and dizzy. Eletriptan (Relpax) is available as a lower-cost generic.

Indications for Relpax

Pros and Cons for Relpax

Pros

Cons

  • Only available as a tablet that's swallowed whole
  • Not recommended for people with severe liver damage
  • Not known if it's safe or works well for children
  • Not used for preventing migraines or treating other types of headaches

Common Side Effects for Relpax

  • Dizziness (up to 6%)
  • Sleepiness (up to 6%)
  • Nausea (up to 5%)
  • Body weakness (up to 5%)
  • "Pins and needles" feeling in the arms or legs (3%)

Warnings for Relpax

  • Heart problems and high blood pressure
  • Stroke or other brain injury
  • Extreme narrowing of blood vessels
  • Worsened headaches if eletriptan (Relpax) is taken too often
  • Serotonin syndrome

Prices with our coupons for Imitrex vs. Relpax

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Sumatriptan1 dose pack / 9 tablets of 100mg
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Eletriptan12 tablets / 40mg
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