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Haldol vs. Trifluoperazine

Haloperidol injection is an antipsychotic medication that's used to treat schizophrenia. It's a long-acting injection that's given into the muscles monthly by a healthcare provider. It's also available as a shorter-acting injection that's typically given in a hospital setting to people who are experiencing agitation related to schizophrenia. The most common side effects of haloperidol injection are movement-related side effects, such as rigid muscles, tremors, and trouble speaking.

• Schizophrenia

• Stiff or rigid muscles, tremors, trouble speaking, and other parkinsonism symptoms (31%)

• Higher risk of death in older people with dementia-related psychosis
• Life-threatening abnormal heart rhythm (QT prolongation)
• Difficulty controlling body movements
• Neuroleptic malignant syndrome (NMS)
• Higher risk of falls
• Pneumonia
• Low white blood cell counts
• Harm to unborn babies

Trifluoperazine is mainly used to manage schizophrenia. It's available as a lower-cost generic medication but it isn't meant for long-term use because it can cause you to have trouble controlling your movements.

• Schizophrenia
• Anxiety

• Drowsiness
• Dizziness
• Skin reactions
• Rash
• Dry mouth
• Trouble falling asleep
• Missing one or more menstrual periods
• Lack of energy

• Death in people age 65 and older with dementia
• Difficulty controlling movements
• Neuroleptic malignant syndrome
• Changes in blood cell counts
• Liver damage
• Low blood pressure and falls
• Vision changes
• High prolactin levels