Key takeaways
Haloperidol (Haldol) and trifluoperazine (Stelazine) are both typical antipsychotics used to treat schizophrenia, but they have some key differences. Haloperidol is available as an oral tablet, oral liquid, and injection, either long-acting or short-acting. In contrast, trifluoperazine is taken orally and usually twice a day. Trifluoperazine can also be used to treat anxiety, but it should not be taken for more than 12 weeks due to the risk of tardive dyskinesia, a condition that causes trouble controlling movements. Both medications carry risks for older adults with dementia-related psychosis, and may cause movement related side effects. Haloperidol can also cause low blood cell counts, while trifluoperazine may cause liver damage.
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