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Haldol vs. Thiothixene

Haloperidol injection is an antipsychotic medication that's used to treat schizophrenia. It's a long-acting injection that's given into the muscles monthly by a healthcare provider. It's also available as a shorter-acting injection that's typically given in a hospital setting to people who are experiencing agitation related to schizophrenia. The most common side effects of haloperidol injection are movement-related side effects, such as rigid muscles, tremors, and trouble speaking.

• Schizophrenia

• Stiff or rigid muscles, tremors, trouble speaking, and other parkinsonism symptoms (31%)

• Higher risk of death in older people with dementia-related psychosis
• Life-threatening abnormal heart rhythm (QT prolongation)
• Difficulty controlling body movements
• Neuroleptic malignant syndrome (NMS)
• Higher risk of falls
• Pneumonia
• Low white blood cell counts
• Harm to unborn babies

Thiothixene is used to treat schizophrenia in people ages 12 years and older. It belongs to a drug class known as typical antipsychotics. This medication comes as a oral capsule and it's typically taken 2-3 times a day. Some of the more common side effects of this medication include drowsiness, restlessness, and uncontrolled body movement. Thiothixene is only available as a generic medication. Brand name Navane has been discontinued.

• Schizophrenia in people ages 12 years and older

• Drowsiness
• Trouble sleeping
• Restlessness
• Uncontrollable body movement

• Higher risk of death in older adults with dementia-related psychosis
• Difficulty controlling muscle movements (tardive dyskinesia)
• Abnormal and prolonged muscle contractions (dystonia)
• Neuroleptic malignant syndrome (NMS)
• Seizures
• Drowsiness and sleepiness
• Low white blood cell count
• Vision changes
• High prolactin levels