Key takeaways
Haldol (haloperidol) and Geodon (ziprasidone) are both antipsychotic medications used to treat schizophrenia, but they have some key differences. Haldol is a typical antipsychotic that works by blocking dopamine activity in the brain and is available in oral forms, as well as an injection, typically given monthly. In contrast, Geodon is an atypical antipsychotic that balances dopamine and serotonin levels and is available as an oral capsule taken by mouth twice daily with food. There's also an injectable form of Geodon to treat agitation caused by schizophrenia. Both medications can cause movement-related side effects, such as rigid muscles and tremors, as well as sleepiness and nausea. Both medications can cause serious side effects like neuroleptic malignant syndrome and heart rhythm problems, but Geodon also carries a risk of weight gain and high blood sugar. Haldol is less likely to cause weight gain compared to other antipsychotics.
