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Compare Duavee vs. Bijuva

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Duavee (conjugated estrogens / bazedoxifene)
    Bijuva (estradiol / progesterone)
  • Duavee (conjugated estrogens / bazedoxifene)
    Bijuva (estradiol / progesterone)

  • Summary of Duavee vs. Bijuva

    Summary for Estrogen replacement / SERM
    Prescription only

    Duavee (conjugated estrogens / bazedoxifene) treats vasomotor symptoms of menopause like hot flashes and night sweats. It can also help prevent osteoporosis in people who've gone through menopause. This combination medication has two active ingredients. The estrogen helps restore estrogen levels in the body while the selective estrogen receptor modulator (SERM) helps protect against bone loss. The dosage is 1 tablet taken by mouth once every day. Side effects can include muscle spasms, nausea, and diarrhea.

    Summary for Estrogen replacement / Progestin
    Prescription only

    Bijuva (estradiol / progesterone) is a medication that combines two hormones into a single pill. It's used to treat moderate-to-severe vasomotor symptoms of menopause like hot flashes and night sweats. It's FDA approved for people with a uterus and have gone through menopause. This medication is a type of menopausal hormone therapy (MHT), also known as hormone replacement therapy (HRT). The dosage is 1 capsule by mouth each night with food. Side effects can include breast tenderness and headaches.

  • Indications of Duavee vs. Bijuva

    Indications for
    •Treatment of moderate-to-severe vasomotor symptoms of menopause (e.g., hot flashes, night sweats)
    •Prevention of osteoporosis in people who've gone through menopause
    Indications for
    •Moderate-to-severe vasomotor symptoms of menopause (e.g., hot flashes, night sweats) in people with a healthy uterus

  • Pros and Cons of Duavee vs. Bijuva

    Pros and Const for Estrogen replacement / SERM
    Pros
    •Relieves bothersome menopause symptoms, such as hot flashes and night sweats
    •Contains an ingredient (bazedoxifene) that helps lower the risk for uterine cancer (no need to take an additional progestin medication)
    Cons
    •Not a first-choice option for preventing osteoporosis in people who've gone through menopause
    •Not recommended for people who haven't gone through menopause, people 75 years or older, or people with kidney problems
    Pros and Const for Estrogen replacement / Progestin
    Pros
    •Only taken once a day
    •Contains progesterone to help lower risk of uterine cancer from the estrogen
    Cons
    •Can take a few weeks to feel the effects of the medication
    •Can cause breast tenderness

  • Common Side Effects of Duavee vs. Bijuva

    Common Side Effects for
    •Muscle spasms or twitching (9%)
    •Nausea (8%)
    •Diarrhea (8%)
    •Indigestion (7%)
    •Upper stomach pain (7%)
    •Throat pain (7%)
    •Dizziness (5%)
    •Neck pain (5%)
    Common Side Effects for
    •Breast tenderness (up to 10%)
    •Headache (up to 4%)
    •Nausea (up to 4%)
    •Vaginal discharge (up to 3%)
    •Vaginal bleeding (3%)
    •Pelvic pain (3%)

  • Warnings of Duavee vs. Bijuva

    Common Side Effects for
    •Risk for blood clots and related complications (e.g., heart attack, stroke)
    •Risk for uterine cancer (also called endometrial cancer)
    •Unknown risk for breast cancer or ovarian cancer
    •Risk for dementia
    •Gallbladder or liver problems in certain people
    •Changes in vision
    •High triglyceride (fat) levels
    •Low thyroid hormone levels in people who take thyroid hormone replacement therapy
    •Buildup of fluids in the body (fluid retention)
    •Worsening of other medical conditions
    Common Side Effects for
    •Risk for blood clots and related complications (e.g., heart attack, stroke)
    •Risk for breast cancer
    •Risk for uterine cancer (also called endometrial cancer)
    •Possible risk of ovarian cancer
    •Risk for dementia
    •Liver or gallbladder problems in certain people
    •Vision problems
    •High triglyceride (fat) levels
    •Buildup of fluids in the body (fluid retention)
    •Low thyroid hormone levels in people who take thyroid hormone replacement therapy
    •Worsening of other medical conditions

  • Prices with our coupons for Duavee vs. Bijuva

    Learn more about Duavee
    Learn more about Bijuva

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