Compare Duavee vs. Divigel
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Duavee (conjugated estrogens / bazedoxifene)Estradiol gel (Divigel)
- Duavee (conjugated estrogens / bazedoxifene)Estradiol gel (Divigel)
Summary of Duavee vs. Divigel
Summary for Estrogen replacement / SERMPrescription onlyDuavee (conjugated estrogens / bazedoxifene) treats vasomotor symptoms of menopause like hot flashes and night sweats. It can also help prevent osteoporosis in people who've gone through menopause. This combination medication has two active ingredients. The estrogen helps restore estrogen levels in the body while the selective estrogen receptor modulator (SERM) helps protect against bone loss. The dosage is 1 tablet taken by mouth once every day. Side effects can include muscle spasms, nausea, and diarrhea.
Summary for Estrogen replacementPrescription onlyEstradiol gel (Divigel) is a hormone replacement therapy used to treat symptoms of menopause, such as hot flashes and night sweats. It comes as single-use packets, and the dose is applied to the skin on your upper thigh once a day. The gel is available as both a brand-name and a generic medication. Common side effects include vaginal yeast infections, breast tenderness, and abnormal vaginal bleeding.
Indications of Duavee vs. Divigel
Indications for•Treatment of moderate-to-severe vasomotor symptoms of menopause (e.g., hot flashes, night sweats)Indications forPros and Cons of Duavee vs. Divigel
Pros and Const for Estrogen replacement / SERMPros•Relieves bothersome menopause symptoms, such as hot flashes and night sweats•Contains an ingredient (bazedoxifene) that helps lower the risk for uterine cancer (no need to take an additional progestin medication)Cons•Not a first-choice option for preventing osteoporosis in people who've gone through menopause•Not recommended for people who haven't gone through menopause, people 75 years or older, or people with kidney problemsPros and Const for Estrogen replacementPros•Relieves bothersome menopausal symptoms, such as hot flashes and night sweats•Applied directly to the skin on the thighs•Only need to use once a day•Available in multiple strengths to customize your doseCons•Raises your risk of certain cancers, blood clots, and strokes•Risk of exposing others to estrogen through skin contact•Might also need to take a progestin medication if you have a uterus•Need to wait for the gel to dry completely before bathing, showering, or swimmingCommon Side Effects of Duavee vs. Divigel
Common Side Effects for•Muscle spasms or twitching (9%)•Nausea (8%)•Diarrhea (8%)•Indigestion (7%)•Upper stomach pain (7%)•Throat pain (7%)•Dizziness (5%)•Neck pain (5%)Common Side Effects for•Abnormal vaginal bleeding (4-10%)•Breast tenderness (3-9%)•Common cold symptoms (4-6%)•Upper respiratory tract infection (2-6%)•Vaginal yeast infection (1-6%)Warnings of Duavee vs. Divigel
Common Side Effects for•Risk for blood clots and related complications (e.g., heart attack, stroke)•Risk for uterine cancer (also called endometrial cancer)•Unknown risk for breast cancer or ovarian cancer•Risk for dementia•Gallbladder or liver problems in certain people•Changes in vision•High triglyceride (fat) levels•Low thyroid hormone levels in people who take thyroid hormone replacement therapy•Buildup of fluids in the body (fluid retention)•Worsening of other medical conditionsCommon Side Effects for•Risk of blood clot•Uterine (endometrial) cancer•Breast cancer•Dementia•Gallbladder and liver problems•Changes in calcium levels in the blood•Vision problems•High triglycerides•Low thyroid hormone levels (hypothyroidism)•Fluid Retention•Worsening of other medical conditions•Potential skin-to-skin transferPrices with our coupons for Duavee vs. Divigel
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