Contrave vs. Ozempic for Weight loss and Diabetes Type 2: Important Differences and Potential Risks.

Contrave

(naltrexone / bupropion)

Ozempic

(semaglutide)

Summary for Contrave

Prescription only

Contrave is a combination medication that helps with weight loss for certain adults. It's taken along with a balanced diet and exercise plan. Contrave is a tablet with two active ingredients that help regulate your appetite. They are naltrexone (an opioid antagonist) and bupropion (a dopamine and norepinephrine reuptake inhibitor). Your dosage will slowly increase over the first 3 weeks. Then, you take the maintenance dose of two tablets by mouth twice a day. Some side effects are nausea, constipation, and headache. But it can also have serious risks, like unusual changes in behavior. Contrave is brand name only; there isn't a generic version available yet.

Indications for Contrave

Long-term weight management in certain adults
- Adults with a body mass index (BMI) of 30 kg/m2 or greater
- Adults with a BMI of 27 kg/m2 or greater and a weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol)

Pros and Cons for Contrave

Pros

Comes as a tablet that you take by mouth
Might start to notice results in as early as 4 weeks (when taken along with a balanced diet and regular exercise)

Cons

Must take twice a day (after the dose ramp-up at the beginning)
Might raise your risk of unusual behavior and thoughts of self-harm
Interacts with a lot of medications

Common Side Effects for Contrave

Nausea (33%)
Constipation (19%)
Headache (18%)
Vomiting (11%)
Dizziness (10%)
Trouble sleeping (9%)
Dry mouth (8%)
Diarrhea (7%)

Warnings for Contrave

Risk of suicidal thoughts and behavior
Possible changes in thoughts, behavior, and mood
Seizures
Don't take Contrave with opioid medications
Higher blood pressure and faster heart rate
Liver problems
Mania (extreme enthusiasm or excitement)
Worsening of glaucoma in certain people
Potential risk of low blood sugar in people taking certain medications for Type 2 diabetes

Summary for Ozempic

Prescription only

Ozempic (semaglutide) is a GLP-1 agonist used with diet and exercise to help adults manage Type 2 diabetes. It can also lower the risk of heart attack, stroke, and heart-related death in some people with Type 2 diabetes. It comes as a once-weekly injection under the skin and as a tablet taken by mouth once a day. The injection is also approved to help slow worsening kidney problems in people with Type 2 diabetes and chronic kidney disease (CKD). Common side effects include nausea, vomiting, and diarrhea.

Indications for Ozempic

Injection:

Type 2 diabetes
Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes and heart disease
Lower the risk of worsening kidney problems and heart-related death in adults with Type 2 diabetes and chronic kidney disease (CKD)

Tablets:

Type 2 diabetes
Lower the risk of heart attack, stroke, and heart-related death in adults with Type 2 diabetes at high risk for these events

Pros and Cons for Ozempic

Pros

Only given once per week
Might help you lose weight
Helps lower the risk of heart problems and kidney problems in people with type 2 diabetes
Available as an injection and an oral tablet

Cons

Commonly causes nausea, vomiting, and diarrhea
Risk of low blood sugar if taken with certain diabetes medications
Can't be used for Type 1 diabetes
Interacts with medications taken by mouth

Common Side Effects for Ozempic

Nausea (16-20%)
Diarrhea (9%)
Vomiting (5-9%)
Stomach pain (6-7%)
Constipation (3-5%)

Note: Side effects listed above are for Ozempic (semaglutide) injection

Warnings for Ozempic

Risk of thyroid tumors
Inflammation of the pancreas (pancreatitis)
Eye problems
Low blood sugar (hypoglycemia) when taken with certain diabetes medications
Kidney damage
Severe stomach problems
Severe allergic reactions
Gallbladder problems
Lung problems during anesthesia or deep sedation

Prices with our coupons for Contrave vs. Ozempic

Contrave120 tablets / 8mg/90mg

$199.20$768.21

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Ozempic30 tablets / 1.5mg

$149.00$1,209.53

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Contrave vs. Ozempic

Contrave

Ozempic

Summary for Contrave

Indications for Contrave

Pros and Cons for Contrave

Pros

Cons

Common Side Effects for Contrave

Warnings for Contrave

Summary for Ozempic

Indications for Ozempic

Pros and Cons for Ozempic

Pros

Cons

Common Side Effects for Ozempic

Warnings for Ozempic

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Contrave

Ozempic

Summary for Contrave

Indications for Contrave

Pros and Cons for Contrave

Pros

Cons

Common Side Effects for Contrave

Warnings for Contrave

Summary for Ozempic

Indications for Ozempic

Pros and Cons for Ozempic

Pros

Cons

Common Side Effects for Ozempic

Warnings for Ozempic