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Botox Cosmetic vs. Jeuveau

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Botox Cosmetic (onabotulinumtoxinA) and Jeuveau (prabotulinumtoxinA-xvfs) are both neuromuscular blockers used to temporarily improve the appearance of frown lines in adults but there are some differences between them. They work by blocking a chemical called acetylcholine, which relaxes the muscles and smooths out wrinkles. However, Botox Cosmetic is also FDA-approved to treat forehead lines and crow's feet, while Jeuveau is only approved for frown lines. Botox Cosmetic can be used for multiple facial areas at once, but Jeuveau is specifically injected into the forehead. The dosing for Botox Cosmetic can vary, with 20 to 40 units per treatment session, whereas Jeuveau typically involves 20 units per treatment session. Both medications are only available as injections administered by a healthcare provider. Common side effects for both medications include headache, pain at the injection site and droopy eyelids. Neither medication is available in a generic form, and both carry risks of serious side effects if the toxin spreads beyond the injection site.

Botox Cosmetic

(onabotulinumtoxinA)

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Jeuveau

(prabotulinumtoxinA)

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Summary for Botox Cosmetic

Prescription only

Botox Cosmetic (onabotulinumtoxinA) is a prescription injection used in adults to temporarily improve the look of facial lines. It's FDA approved to treat moderate to severe frown lines between the eyebrows, forehead lines, crow’s feet, and neck lines. The medication is injected directly into the facial muscles by a trained healthcare professional. Side effects can vary depending on the injection site and can include headache and droopy eyelids.

Botox Cosmetic (onabotulinumtoxinA) is different from medical Botox, which is used for certain health conditions like migraines or muscle spasms.

Indications for Botox Cosmetic

Temporarily improves the appearance of moderate to severe facial lines, including:

  • Frown lines
  • Crow's feet
  • Forehead lines
  • Neck lines

Pros and Cons for Botox Cosmetic

Pros

  • Can treat many facial and neck lines at the same time
  • Might start to see results within days
  • Lasts up to 3 to 4 months
  • Quick recovery time after injections

Cons

  • Needs to be injected by a trained healthcare professional
  • Injections can be uncomfortable
  • Not permanent, requires repeat injections
  • Side effects include droopy eyelids and headache

Common Side Effects for Botox Cosmetic

Frown lines:

  • Droopy eyelids (3%)

Crow's feet:

  • Eyelid swelling (1%)

Forehead lines:

  • Headache (9%)

Warnings for Botox Cosmetic

  • Spread of toxin effect
  • Serious allergic reaction
  • Heart-related side effects
  • Difficulty swallowing or breathing
  • Eye and vision problems
  • Transmission of diseases

Summary for Jeuveau

Prescription only

Jeuveau (prabotulinumtoxinA or prabotulinumtoxinA-xvfs) is a neuromuscular blocker made of botulism toxin. It's injected into certain muscles on the forehead to improve the looks of frown lines in adults. If you need more than one treatment, your HCP can inject Jeuveau (prabotulinumtoxinA) at most once every 3 months. Jeuveau (prabotulinumtoxinA) should only be given by a licensed healthcare professional (HCP) in a healthcare setting. Some common side effects of this medication include headache and pain at the injection site.

Indications for Jeuveau

  • Temporary improvement in moderate-to-severe frown lines (glabellar lines) in adults

Pros and Cons for Jeuveau

Pros

  • Works well to improve the appearance of moderate-to-severe frown lines
  • Injected directly at the affected area on the forehead
  • Effects can last many months after each treatment

Cons

  • Results aren't permanent, might need re-treatment
  • Can experience headaches as side effects
  • Unknown if safe to use during pregnancy or breastfeeding

Common Side Effects for Jeuveau

  • Headache (12%)
  • Upper respiratory tract infection (e.g., common cold; 3%)
  • Drooping eyelid (2%)

Warnings for Jeuveau

  • Spread of toxin effects
  • Severe allergic reactions
  • Difficulty swallowing or breathing
  • Worsening of certain conditions
  • Dry eyes

Prices with our coupons for Botox Cosmetic vs. Jeuveau

Price Card Drug Icon
Botox Cosmetic1 vial / 50 units
$363.61$459.24
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Price Card Drug Icon
Jeuveau1 vial / 100 units
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