Key takeaways
Aimovig (erenumab) and Botox (onabotulinumtoxinA) are both used to prevent migraines, but they work in different ways and have different uses. Aimovig is a calcitonin gene-related peptide (CGRP) receptor antagonist that blocks proteins involved in migraine pain signaling and is available as a monthly injection that you can do at home. Botox is a neuromuscular blocker thought to affect pain-causing chemicals in the brain and must be given by a healthcare professional every three months. Both are only available as a brand-name medications; however, Botox also has a cosmetic version used to treat wrinkles. Aimovig is approved for migraine prevention in adults, whereas Botox has multiple uses, including treating muscle spasms, bladder issues, and excessive sweating. Common side effects for Aimovig include injection site reactions and constipation. Using Botox can cause urinary tract infections, neck pain, and muscle weakness. Additionally, Botox carries serious risks if the toxin spreads to other parts of the body, which is not a concern with Aimovig.
