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PCSK9 Inhibitors

PCSK9 Inhibitors may be used to treat high cholesterol. They also may be used to lower the risk of heart attack and stroke in people with coronary artery disease. These medications work by blocking the PCSK9 protein, which helps the liver get rid of cholesterol from the blood.

Why are pcsk9 inhibitors prescribed?

  1. High Cholesterol (66%)
  2. Stroke Risk Reduction (11%)
  3. Heart Attack (11%)
  4. Coronary Artery Disease (11%)

Key takeaways

PCSK9 inhibitors are used to treat high cholesterol and familial hypercholesterolemia. They can also help reduce the risk of heart attack and stroke in people with heart disease. These medications work by blocking a protein in the body called PCSK9, which then helps your liver remove more LDL cholesterol (the "bad" cholesterol) from your blood. PCSK9 inhibitors are injectable medications. Examples include Repatha (evolocumab) and Praluent (alirocumab). You will need to get these injections regularly to keep your cholesterol levels in check.

Prices for popular PCSK9 Inhibitors medications
Viewing 2 of 2 medications
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Repatha

as low as$581
EVOLOCUMAB treats high cholesterol. It may also be used to lower the risk of heart attack, stroke, and a type of heart surgery. It works by decreasing bad cholesterol (such as LDL) in your blood. It is a monoclonal antibody. Changes to diet and exercise are often combined with this medication.
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Praluent

as low as$441
Praluent (alirocumab) is a PCSK9 inhibitor. It is used to lower the level of cholesterol in the blood, and cut the risk of heart attacks, stroke and other major cardiovascular events. This medicine is only for patients whose cholesterol is not controlled by diet and statin therapy. Praluent is less popular than other PCSK9 Inhibitors. There are currently no generic alternatives to Praluent.

GoodRx has partnered with Inside RX and Regeneron Pharmaceuticals to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Praluent is not covered by most Medicare and insurance plans.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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