Key takeaways
Fenofibrate (brand names: Fenoglide, Trilipix, Antara, Tricor, Lipofen) and rosuvastatin (brand names: Crestor, Ezallor Sprinkle) are both used to manage cholesterol levels, but they belong to different classes of medications. Fenofibrate is a fibrate that primarily lowers triglycerides and raises "good" cholesterol (HDL), while rosuvastatin is a statin that mainly lowers "bad" cholesterol (LDL) and also raises HDL. Fenofibrate is available in various forms, including capsules and tablets, and can be taken at any time of day. Rosuvastatin, available as a generic, can be taken with or without food and is also available in a sprinkle form for those who have trouble swallowing pills. Common side effects of fenofibrate include liver problems and stomach pain, whereas rosuvastatin commonly causes muscle pain and headaches. Both medications can cause serious muscle damage and liver issues, but rosuvastatin may also raise blood sugar levels. Neither medication is recommended during pregnancy or breastfeeding.
