Skip to main content
Drug bottle and Pill

Compare Tricor vs. Vytorin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fenofibrate (brand names: Fenoglide, Trilipix, Antara, Tricor, Lipofen) and Vytorin (generic name: ezetimibe/simvastatin) are both used to manage cholesterol levels, but they work in different ways and belong to different drug classes. Fenofibrate is a fibrate that primarily lowers triglycerides and "bad" cholesterol (LDL) while raising "good" cholesterol (HDL). It is taken once daily and is available in various forms, including generics. Vytorin combines ezetimibe, a cholesterol absorption inhibitor, and simvastatin, a statin, to lower "bad" cholesterol and triglycerides while raising "good" cholesterol. Vytorin is also taken once daily, preferably in the evening, and is available in a generic form. Fenofibrate is used cautiously with statins due to the risk of muscle damage, whereas Vytorin already includes a statin and carries a risk of muscle breakdown (rhabdomyolysis). Both medications require you to follow a healthy diet and regular exercise for the best results. Fenofibrate is not recommended during pregnancy or breastfeeding, and Vytorin is also unsafe for pregnant or nursing individuals.

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.