Repatha vs. Praluent for High Cholesterol: Important Differences and Potential Risks.

Repatha

(evolocumab)

Praluent

(alirocumab)

Summary for Repatha

Prescription only

Repatha (evolocumab) is a PCSK9 inhibitor that's given as an injection under the skin. It treats high cholesterol in adults and certain children. It works best with a heart-healthy diet and regular exercise. Repatha (evolocumab) also helps lower the risk of events like heart-related death, heart attack, and stroke in adults at risk. The medication is injected either once every 2 weeks or once a month. Side effects can include common cold symptoms and discomfort at the injection site.

Indications for Repatha

High cholesterol in adults
Heterozygous familial hypercholesterolemia (HeFH) in people ages 10 years and older
Homozygous familial hypercholesterolemia (HoFH) in people ages 10 years and older
Lowering the risk of heart-related death, heart attack, stroke, hospitalization for chest pain, and the need for heart procedures in adults at risk

Pros and Cons for Repatha

Pros

Taken once every 2 weeks or once a month
Can use for inherited cholesterol conditions in kids 10 years and up
Has different injection devices to choose from (prefilled syringe, autoinjector, or on-body infusor)

Cons

Must give as an injection under the skin
Might cause reactions at the injection site like redness and pain
Caution use in people with a latex allergy for syringes and autoinjectors (some have parts made with natural rubber)

Common Side Effects for Repatha

Common cold symptoms (4%)
Back pain (2%)
Upper respiratory tract infection (2%)
Joint pain (2%)
Nausea (2%)
Tiredness (2%)

Warnings for Repatha

Allergic reactions

Summary for Praluent

Prescription only

Praluent (alirocumab), is a PCSK9 inhibitor used to treat high cholesterol in certain adults and children, including those with a genetic condition called familial hypercholesterolemia. The medication also helps lower the risk of heart attack, stroke, and hospitalization for chest pain in adults with heart disease. Praluent (alirocumab) is injected under the skin in the thigh, stomach, or upper arm every 2 weeks or 4 weeks, depending on your dose. Common side effects include injection-site reactions, flu or flu-like symptoms (e.g. sneezing, coughing, runny nose), and diarrhea.

Indications for Praluent

Lower the risk of heart attack, stroke, and hospitalization for chest pain (angina) in adults with heart disease
High cholesterol (including heterozygous familial hypercholesterolemia (HeFH)) in adults, alone or with diet and other cholesterol-lowering medications
Homozygous familial hypercholesterolemia (HoFH) in adults, along with other cholesterol-lowering medications
Heterozygous familial hypercholesterolemia (HeFH) in children ages 8 and older, along with diet and other cholesterol-lowering medications

Pros and Cons for Praluent

Pros

Lowers LDL ("bad") cholesterol by about 50% to 60%
Reduces the risk of heart problems in adults with heart disease
Used alone or with other cholesterol-lowering medications
Given either every 2 or 4 weeks

Cons

Must be injected under the skin
Side effects include injection-site reactions, flu, and diarrhea
Potential for serious allergic reactions
Not known if safe during pregnancy or breastfeeding

Common Side Effects for Praluent

Injection-site reactions (7%)
Flu or flu-like symptoms (6%)
Diarrhea (5%)

Warnings for Praluent

Serious allergic reaction

Prices with our coupons for Repatha vs. Praluent

Repatha2 sureclicks / 1ml of 140mg/ml

$239.00$691.00

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Praluent1 carton / 2 pens of 75mg/ml

$225.00$635.99

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Repatha vs. Praluent

Repatha

Praluent

Summary for Repatha

Indications for Repatha

Pros and Cons for Repatha

Pros

Cons

Common Side Effects for Repatha

Warnings for Repatha

Summary for Praluent

Indications for Praluent

Pros and Cons for Praluent

Pros

Cons

Common Side Effects for Praluent

Warnings for Praluent

Prices with our coupons for Repatha vs. Praluent

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Repatha

Praluent

Summary for Repatha

Indications for Repatha

Pros and Cons for Repatha

Pros

Cons

Common Side Effects for Repatha

Warnings for Repatha

Summary for Praluent

Indications for Praluent

Pros and Cons for Praluent

Pros

Cons

Common Side Effects for Praluent

Warnings for Praluent