What should I watch for?
Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.
Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help. Contact your doctor if the problem does not go away or is severe.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- black, tarry stools
- breathing problems
- changes in vision
- chest pain
- eye pain
- fast, irregular heartbeat
- feeling faint or lightheaded, falls
- hallucination, loss of contact with reality
- loss of balance or coordination
- loss of memory
- restlessness, pacing, inability to keep still
- stiff muscles
- suicidal thoughts or other mood changes
- trouble sleeping
- unusual bleeding or bruising
- unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
- certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- methylene blue (injected into a vein)
This medicine may also interact with the following medications:
- aspirin and aspirin-like medicines
- certain medicines for depression, anxiety, or psychotic disturbances
- certain medicines for infections like chloroquine, clarithromycin, erythromycin, furazolidone, isoniazid, pentamidine
- certain medicines for migraine headaches like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
- certain medicines for sleep
- certain medicines that treat or prevent blood clots like dalteparin, enoxaparin, warfarin
- NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)
- supplements like St. John's wort, kava kava, valerian