How Much Is Breztri Aerosphere Without Insurance?
A Breztri Aerosphere inhaler can cost around $700 if you do not have insurance. Learn about ways you can save on Breztri Aerosphere.
Breztri Aerosphere
Used for Asthma, COPD
Used for Asthma, COPD
Breztri Aerosphere is a triple therapy inhaler. It contains budesonide (an inhaled corticosteroid), glycopyrrolate (a long-acting muscarinic antagonist), and formoterol fumarate (a long-acting beta agonist). It's used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It's also approved for the maintenance treatment of asthma in people 12 years and older. Breztri is inhaled through the mouth twice each day. Common side effects include upper respiratory tract infections and pneumonia.
What is Breztri?
What is Breztri used for?
- Maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults
- Maintenance treatment of asthma in adults and children 12 years of age and older
How Breztri works
Breztri is a combination inhaler. It contains three medications that work together to help you breathe more easily.
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Budesonide is an inhaled corticosteroid. It's thought to lower inflammation in your lungs.
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Glycopyrrolate is a long-acting muscarinic antagonist (LAMA). It helps prevent your airways from tightening. This helps keep your airways open.
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Formoterol fumarate is a long-acting beta agonist (LABA). It relaxes the muscles in your lungs. This helps open up your airways and helps you breathe more easily.
When does Breztri start working?Time passed since treatment started:
Drug facts
| Common Brands | Breztri Aerosphere |
|---|---|
| Drug Class | ICS / LAMA / LABA |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
More on Breztri essentials
Side effects of Breztri
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Less Common Side Effects
COPD:
- Back pain
- Oral thrush
- Flu
- Muscle spasms
- Urinary tract infection
- Cough
- Sinus infection
- Diarrhea
Asthma:
- Pneumonia
- Headache
Breztri serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: hives; swelling of your face, lips, or tongue; trouble breathing
- Sudden tightening of your airways: trouble breathing, wheezing, cough, chest pain or tightness
- Thrush: white patches in your mouth, cotton-like feeling in your mouth, pain while eating or swallowing, loss of taste
- Heart problems: dizziness, fatigue, tremor, nausea, rapid heartbeat, weakness, trouble sleeping
When do Breztri possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Cough
Throat irritation
Risk of oral thrush
Risk of respiratory infections
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.
The following Breztri side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Increase in blood pressure
- Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
- Muscle pain or cramps
- Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
- Thrush—white patches in the mouth
- Trouble passing urine
- Wheezing or trouble breathing that is worse after use
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Change in taste
- Constipation
- Cough
- Dry mouth
- Headache
- Hoarseness
- Runny or stuffy nose
- Sore throat
- Tremors or shaking
- Trouble sleeping
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$847.96
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Pros and cons of Breztri
Pros
- Helps lower the risk of COPD flare-ups in adults
- Helps lower the risk of asthma attacks in people 12 years and older
- Combination of three medications in a single inhaler
- Can use with a spacer to help make inhaling the medication easier
Cons
- Need to take 2 puffs twice each day
- Need to rinse your mouth after each use
- Might cause throat irritation or hoarseness
- Doesn't treat sudden COPD or asthma attacks
Pharmacist tips for Breztri
- Take 2 puffs of Breztri in the morning and 2 puffs in the evening every day. It's a good idea to use the inhaler at around the same times each day. This can help you remember when to use your Breztri inhaler and help the medication work consistently.
- How to prime your Breztri inhaler: Before using a new Breztri inhaler, shake it well and spray into the air 4 times away from your face. Shake it before each spray. If you haven't used your inhaler for 7 days or more or if you've cleaned it, spray it into the air 2 times before using it again. Priming the inhaler helps make sure you get your full dose.
- How to use Breztri: Remove the cap and make sure there isn't anything in the mouthpiece. Shake the inhaler well before each puff. Breathe out fully, place the mouthpiece in your mouth, and close your lips around it. As you slowly take a deep breath in, press down on the canister for a puff. Try to hold your breath for as long as you comfortably can (up to 10 seconds). This helps the medication reach deep into your lungs. Then, breathe out. Repeat for your second puff.
- Rinse your mouth after using Breztri: Rinse your mouth with water and spit it out after taking your 2 puffs. This helps lower your risk of thrush in your mouth or throat.
- Don't use Breztri to treat a sudden COPD or asthma attack. Be sure you have your rescue inhaler handy to help with sudden trouble breathing. Breztri won't work fast enough to help in these situations.
- Call your prescriber if your breathing get worse while using Breztri. Also tell them if you need to use your rescue inhaler more often than usual. These can be signs that Breztri isn't controlling your asthma or COPD well enough. Your prescriber can see if they need to adjust your treatment to help control your symptoms better.
- Tell your care team about all the medications and supplements you take and plan to take. They can help you check for interactions with Breztri and keep you safe. Some interactions can raise your risk of side effects or make Breztri not work well. These medications can include anticholinergics, beta blockers, ketoconazole, and tricyclic antidepressants like amitriptyline.
- How to clean your Breztri inhaler: Clean the inhaler once a week to prevent medication from building up in the mouthpiece. Remove the mouthpiece and canister and set them aside. Then, run warm water through the mouthpiece and the top of the inhaler for 30 seconds each. Shake off any extra water and let it fully air dry before putting your inhaler back together.
- When to throw away Breztri: Throw away the inhaler when the dose counter reaches "0" in the red zone. Or, throw it away 3 months after opening the 120-puff inhaler or 3 weeks after opening the 28-puff inhaler. Follow whichever comes first, even if there's medication left.
- When to get a refill for Breztri: Get a refill when the dose counter reaches the yellow zone. This means you're running low on puffs in your Breztri inhaler. You should get a refill so you don't run out of medication.
- How to store Breztri: Store the inhaler at room temperature (68ºF to 77ºF). Keep it in a dry place away from heat, sunlight, and open flames. Keep unused inhalers in the original foil pouch.
Risks and warnings for Breztri
Breztri can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Not for flare-ups or worsened breathing
Don't use Breztri to treat sudden breathing problems or flare-ups. It doesn't work fast enough to help in these situations. Use your rescue inhaler, such as albuterol, if you suddenly have trouble breathing.
Tell your prescriber if you need to use your rescue inhaler more often than usual. This can be a sign that your COPD or asthma is getting worse.
Also, don't use more Breztri than prescribed. This won't help you breathe better and can raise your risk of side effects, such as a fast heartbeat, shaking, or dizziness. Your prescriber can adjust your treatment to help control your symptoms better.
Sudden tightening of your airways (bronchospasm)
In rare cases, inhaled medications like Breztri can cause the airways to suddenly tighten. This can cause trouble breathing, wheezing, cough, or chest tightness and can be life-threatening. If this happens after using Breztri, use your rescue inhaler and get medical help right away.
Fungal infection in the mouth
- Risk factors: Not rinsing and spitting after using Breztri | Weakened immune system from medical conditions or medications
Breztri contains budesonide, a steroid medication. When inhaled, it can cause a fungal infection in your mouth and throat called thrush. The risk is highest during the first 3 months after you start Breztri.
Rinse your mouth with water and spit after each time you use Breztri. This helps lower your risk of thrush. Still, be sure to watch for symptoms of thrush. It can include white patches in your mouth, cotton-like feeling in your mouth, pain while eating or swallowing, or loss of taste. Tell a healthcare professional if this happens.
If you develop thrush, your prescriber might give you medications to treat it. They might also ask you to temporarily stop using Breztri until it goes away.
Higher risk of infections
- Risk factors: Active infection | Taking other medications that can weaken your immune system
Breztri contains a steroid, which can weaken your immune system. This can raise your risk of infections, including upper respiratory infections and pneumonia. It also might affect how well you can fight an infection.
Tell your prescriber if you have any active, untreated, or long-term infections. This includes tuberculosis (TB) or a herpes eye infection. Watch for any signs of new or worsening infection, like fever, chills, or body aches. Your prescriber can help decide if Breztri is right for you. They might choose a different medication until your infection is treated.
Steroid effects from overuse and switching from steroid pills
- Risk factors: Using Breztri for a long time | Using too much Breztri
Use Breztri only as directed. Don't use more than the maximum number of puffs each day. Otherwise, more of the steroid in Breztri can be absorbed into your body. This can raise your risk of certain side effects from steroids, such as high blood sugar or high blood pressure.
And if you're switching from steroid pills to Breztri, your body might need time to adjust. Stopping steroid pills too quickly can cause symptoms like stomach pain, loss of appetite, or nausea. Your prescriber will work with you to slowly lower your steroid pill dose while switching to Breztri to help prevent these side effects.
Allergic reactions
Allergic reactions to Breztri are possible. This can be sometimes include anaphylaxis and can be life-threatening. Get medical help right away if you notice hives or rash. Also call 911 right away if you notice swelling of the face, lips, or tongue or having trouble breathing or swallowing. These can be signs of a serious allergic reaction.
Effects on heart rate, heart rhythm, and blood pressure
- Risk factors: High blood pressure | Heart failure | Heart rate or rhythm problems | Using more Breztri than recommended
Breztri contains formoterol. In some people, formoterol can cause changes in blood pressure, heart rate, or heart rhythm. These side effects are uncommon and are less likely to happen when you use Breztri as directed.
Before starting Breztri, tell your prescriber if you have heart problems or high blood pressure. They can make sure the medication is safe for you. They might ask you to regularly check your blood pressure and heart rate at home.
Don't use Breztri more often or at higher doses than recommended. Also, don't use other inhalers that contain a LABA (medications similar to formoterol) at the same time. This can raise your risk of serious heart-related side effects.
Let your prescriber know if you have dizziness, fatigue, tremor, a fast heartbeat, or weakness while using Breztri, let your prescriber know. These could be signs of changes in your heart rate or blood pressure. Your prescriber can check out what's going on.
Weaker bones
- Risk factors: Using Breztri long term | Older adults | Can't move for a long time | Family history of osteoporosis | Menopause | Tobacco use | Poor nutrition | Taking medications that can cause bone loss
Using Breztri for a long time might make your bones weaker. This might not always lead to broken bones. But it can be a concern if you have risks like being older, going through menopause, smoking, eating poorly, or taking certain medications.
People with COPD often have some of these risk factors. Because of this, your prescriber might check your bone health before and during your Breztri treatment. If your bones are getting too weak and you still need this inhaler, your prescriber can suggest ways to help protect your bones.
Slowed growth in children
Inhaled steroids, like the budesonide in Breztri, can cause slowed growth in children. The care team will check your child's growth during treatment to make sure they're on track. Talk to your child's prescriber if you have concerns about your child's growth.
Eye and vision problems
- Risk factors: Long-term use of Breztri | History of glaucoma | History of high eye pressure
Breztri contains budesonide, a steroid, and glycopyrrolate, an anticholinergic. Rarely, people using inhaled steroids or anticholinergics for a long time have had eye problems. This can include higher eye pressure, glaucoma, or cataracts.
Before starting Breztri, tell your prescriber if you have glaucoma or cataracts. If you need to use the inhaler for a long time, they might recommend regular eye exams.
Look out for any eye pain or discomfort, blurry vision, cloudy vision, or halos around lights. If you notice this while using Breztri, call your prescriber or eye specialist right away.
Trouble urinating
- Risk factors: Enlarged prostate | Bladder-neck obstruction (blockage)
Tell your prescriber if you have prostate problems or trouble emptying your bladder. Breztri contains glycopyrrolate, which can make these problems worse.
Let your prescriber know if you have more trouble urinating or pain when you urinate while using Breztri. They can help figure out what's going on and decide what to do next.
Low potassium and high blood sugar
Breztri can sometimes lower your potassium levels. This is usually mild and should go back to usual with time. Low potassium can cause tiredness, weakness, muscle cramps, a fast heartbeat, or a tingling feeling in your hands and feet. Tell your prescriber if you notice any of these symptoms while using Breztri.
Breztri can also sometimes raise blood sugar levels. This is usually temporary. Talk with your prescriber if you're concerned, particularly if you have diabetes.
Caution use in people with certain health conditions
- Risk factors: Symptoms of high thyroid hormone levels | History of seizures
Before using Breztri, be sure to share your full medical history with your prescriber. This is especially important if you have a history of seizures or symptoms of high thyroid hormone levels. Breztri can sometimes make certain conditions worse or lead to serious side effects. Your prescriber can help decide if this inhaler is safe for you and help monitor you better.
Breztri dosage
The average cost for 1 inhaler of 120 inhalations of 160mcg/9mcg/4.8mcg of Breztri is $0.00 with a free GoodRx coupon. This is 100.00% off the average retail price of $847.96. 
Inhaler
Inhaler| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 120 inhalations of 160mcg/9mcg/4.8mcg | 1 inhaler | $0.00 | $0.00 |
| 120 inhalations of 160mcg/18mcg/4.8mcg | 1 inhaler | $0.00 | $0.00 |
Typical dosage for Breztri
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COPD: Use the Breztri inhaler with 160 mcg of budesonide/9 mcg of glycopyrrolate/4.8 mcg of formoterol fumarate.
- Adults: The typical dose is 2 inhalations by mouth twice each day (in the morning and in the evening).
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Asthma: Use the Breztri inhaler with 160 mcg of budesonide/18 mcg of glycopyrrolate/4.8 mcg of formoterol fumarate.
- Adults and children 12 years and older: The typical dose is 2 inhalations by mouth twice each day (in the morning and in the evening).
How much does Breztri cost?
To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Breztri Aerosphere (brand)
$0.00
Breztri contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Breztri will not be safe for you to take.
- Treatment of sudden trouble breathing
- Allergy to budesonide, glycopyrrolate, or formoterol
What are alternatives to Breztri?
There are a number of medications that your doctor can prescribe in place of Breztri. Compare a few possible alternatives below.
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