SNRIs are used to elevate mood to treat depression, anxiety, diabetic neuropathy, fibromyalgia, musculoskeletal conditions, and panic disorder. They work by increasing levels of serotonin and norepinephrine in the brain.

Why are
SNRIs
prescribed?

How is this chart calculated?

How we make this chart

This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition.

Prices for Popular SNRIs

Popularity Brand Name (Generic Name) GoodRx Fair Price Price Trend
Cymbalta
(duloxetine)
19
See Prices
Duloxetine (Cymbalta) is a moderately priced drug used to treat depression, anxiety, fibromyalgia, and nerve pain associated with diabetes (diabetic peripheral neuropathy). It is more popular than comparable drugs. As of 2013, it is available in generic and brand versions. Generic duloxetine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Effexor XR
(venlafaxine er)
11
See Prices
Effexor XR (venlafaxine ER) is an extended-release SNRI used to treat depression, anxiety, and panic disorder. It works by increasing the amount of serotonin and norepinephrine available in the brain. Effexor XR is available as generic venlafaxine ER. Immediate release venlafaxine is also available, though regular Effexor has been discontinued.
venlafaxine
25
See Prices
Venlafaxine is a generic SNRI used to treat depression. It works by increasing the amount of serotonin and norepinephrine available in the brain. Brand name venlafaxine was known as Effexor and has been discontinued. An extended release version, Effexor XR (venlafaxine ER) is available as a brand and generic.
Pristiq
299
See Prices
Desvenlafaxine (Pristiq) is an expensive drug used to treat depression. This drug is slightly less popular than comparable drugs. A generic form of Pristiq may become available in 2022. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
Savella
300
See Prices
MILNACIPRAN is used to treat the pain caused by fibromyalgia.
Fetzima
307
See Prices
Levomilnacipran is used to treat depression.
Khedezla
(desvenlafaxine er)
256
See Prices
DESVENLAFAXINE is used to treat depression.
desvenlafaxine succinate ER
N/A N/A See Prices
Desvenlafaxine Fumarate ER
132
See Prices
DESVENLAFAXINE is used to treat depression.

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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