Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Cymbalta (duloxetine) and fluvoxamine are both prescription medications, but they belong to different drug classes and treat different conditions. Cymbalta is an SNRI (serotonin and norepinephrine reuptake inhibitor) used to treat depression, anxiety, and various types of long-term pain, including diabetic neuropathy and fibromyalgia. On the other hand, fluvoxamine is an SSRI (selective serotonin reuptake inhibitor) primarily used to treat obsessive-compulsive disorder (OCD) in adults and children aged 8 years and older. Cymbalta is typically taken once daily, while fluvoxamine can be taken once or twice daily depending on the form and dose. Both medications can cause side effects like nausea and headache, but fluvoxamine is more likely to cause sleep problems and has a higher risk of drug interactions. Additionally, Cymbalta can be taken at any time of day, whereas fluvoxamine is often taken at bedtime to help manage drowsiness. Both medications are available in generic forms, making them more affordable options.
Duloxetine (Cymbalta)
Fluvoxamine
Duloxetine (Cymbalta)
Fluvoxamine
Summary of Cymbalta vs. Luvox
Summary for SNRI
Prescription only
Duloxetine (Cymbalta) helps treat depression and anxiety. It can also help with some types of chronic pain, such as nerve pain from diabetes. Duloxetine (Cymbalta) is a type of antidepressant called an SNRI, or serotonin and norepinephrine reuptake inhibitor. Most people take it by mouth once a day, but some with depression might take it twice a day. Side effects include nausea, headache, and dry mouth. When it's time to stop taking the medication, the prescriber will slowly lower your dose to help prevent withdrawal symptoms.
Summary for SSRI
Prescription only
Fluvoxamine maleate is an SSRI, or a selective serotonin reuptake inhibitor. It's approved to treat obsessive-compulsive disorder (OCD) in people ages 8 years and up. Fluvoxamine comes as immediate-release tablets taken by mouth once or twice a day. For adults, it also comes as extended-release capsules taken once a day. Your specific dosage depends on which form you're taking. Side effects include nausea, sleepiness or trouble sleeping, and headache. Fluvoxamine is a generic medication; the brand name Luvox is no longer available.