Key takeaways
Clomipramine (Anafranil) and fluvoxamine (Luvox) are both used to treat obsessive-compulsive disorder (OCD), but they belong to different medication classes. Clomipramine is a tricyclic antidepressant (TCA), while fluvoxamine is a selective serotonin reuptake inhibitor (SSRI). Clomipramine can be used in children as young as 10 years old, whereas fluvoxamine can be used in children as young as 8 years old. Clomipramine often causes side effects like dry mouth, sleepiness, and weight gain, while fluvoxamine commonly causes nausea, sleep problems, and headache. Fluvoxamine is considered a first-choice treatment for OCD, but clomipramine is not due to its higher risk of side effects. Additionally, fluvoxamine has a higher risk of medication interactions compared to clomipramine. Both medications are available in generic forms, making them more affordable options.
