Compare Paxil vs. Celexa

Paroxetine (Paxil) and citalopram (Celexa) are both selective serotonin reuptake inhibitors (SSRIs) used to treat depression, but they have some differences. Paroxetine is available in both immediate-release and extended-release forms. It can treat a wider range of conditions, including anxiety disorders, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Citalopram is primarily used for depression and is considered a first-choice option for this condition. Paroxetine is more likely to cause weight gain and sexual side effects compared to citalopram, which has a lower risk for weight gain. Both medications can cause withdrawal symptoms if stopped suddenly and can interact with other medications, especially those affecting serotonin levels. Additionally, both can cause serious side effects like serotonin syndrome and a serious heart rhythm problem called QT prolongation.