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Nystatin Coupon - Nystatin 100000 units/ml ml of oral suspension

nystatin topical

Generic Nyamyc
Used for Candidiasis, Thrush, Yeast Infection

Nystatin topical is a prescription antifungal you use on your skin to treat certain fungal skin infections, like yeast infections. It's safe for all ages, even babies with diaper rash. Nystatin topical comes as a cream, ointment, or powder. You usually apply it to the affected skin 2 to 3 times a day. Sometimes, it can cause mild side effects like itching or burning where you put it on.

Reviewed by:Last reviewed on September 6, 2025
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What is Nystatin topical?

What is Nystatin topical used for?

How Nystatin topical works

Nystatin topical is an antifungal. It works by breaking down the protective covering of the fungus. This stops the fungus from growing and kills it, helping to clear the infection.

When does Nystatin topical start working?Time passed since treatment started:
HOURS
DAYS
Initial effect
WEEKS
Full effect
MONTHS

Drug facts

Common BrandsNystop, Nyamyc, Klayesta
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Nystatin topical

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Burning or pain where applied
  • Itching
  • Rash
  • Eczema

Nystatin topical serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: rash or hives, swelling of your face or throat, chest tightness, trouble breathing
When do Nystatin topical possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Burning feeling on skin
Eczema

Source: DailyMed

The following Nystatin topical side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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Pros and cons of Nystatin topical

Pros

  • Comes as an ointment, cream, and powder
  • Generally well-tolerated with few side effects
  • Safe for all ages, including babies

Cons

  • Applied onto skin multiple times a day
  • Only treats some fungal skin infections, not bacteria or viruses
  • Need a prescription to get it
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Pharmacist tips for Nystatin topical

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  • You'll usually apply nystatin topical 2 or 3 times a day, but always follow the exact instructions from your prescriber. Skipping doses can make your infection last longer.
  • Make sure to finish your full course of nystatin topical, even if your skin looks better. Stopping the medication too early can cause your infection to come back and be harder to treat.
  • Use nystatin topical only on your skin. Don't put the medication in your eyes, nose, or ears. Never put it inside the vagina to treat a vaginal yeast infection.
  • Wash your hands before and after applying nystatin topical to help prevent getting the medication in your eyes. If it does get in your eyes, rinse your eyes with water or saline and call your prescriber if the irritation doesn’t go away.
  • Some mild burning or itching can happen after using nystatin topical. But if you notice a rash or have side effects that don't go away, contact your prescriber.
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Common questions about Nystatin topical

No, nystatin topical isn't an antibiotic. It's an antifungal, which means it treats skin infections caused by fungi. It doesn't work for bacterial infections.

Nystatin topical isn't sold over the counter. You'll need a prescription from your healthcare professional to get it from the pharmacy.

Yes, nystatin topical can help with itching if the itching is caused by a fungal infection on your skin. It works by killing the fungus that causes the infection, which can relieve symptoms like redness, irritation, and itching. If your itching doesn’t improve or gets worse, let your prescriber know because you might need a different treatment.

Nystatin topical usually starts to relieve symptoms within the first few days. In particular, the topical ointment can begin working in as little as 24 to 72 hours. How long you’ll need to use it depends on the type and how serious your infection is. Even if your symptoms start to improve, be sure to finish your full treatment so the infection goes away completely.

Yes, nystatin topical can be used on the irritated skin on the outside of the groin to treat certain fungal infections, such as diaper rash. You can apply it to the skin in that area, but don’t put it inside the vagina. If the area stays very moist, the powder form might work better than the cream or ointment. Ask your prescriber if you’re not sure which option is best for you.

Studies show that nystatin topical doesn't work well for treating ringworm, so dermatologists don't usually prescribe it. Other antifungal medications are much more effective and are available both over the counter and by prescription.

You shouldn't use nystatin topical if you've ever had an allergic reaction to it or any of its ingredients. You also shouldn’t use it for infections it doesn’t treat, like bacterial or viral infections, because it won’t help. Always check with your prescriber before using nystatin topical to make sure it’s the right medication for your condition.

No, nystatin topical isn't a steroid. Steroids are usually used to relieve skin irritation due to eczema, allergies, or other causes of skin inflammation. Nystatin topical is an antifungal medication that treats yeast infections on the skin by targeting the fungus itself. If you aren't sure which topical product is right for you, talk to your prescriber.

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Risks and warnings for Nystatin topical

Nystatin topical can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Use only on your skin

Nystatin topical should only be used on your skin to treat certain fungal infections. Don’t put it in your eyes, nose, mouth, or ears, and never put it inside the vagina. If you think that your child might’ve accidentally swallowed this medication, call your Poison Control Center at 1-800-222-1222 as soon as possible.

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Nystatin topical dosage

The average cost for 200 ml of 100000 units/ml of Nystatin topical is $17.80 with a free GoodRx coupon. This is 82.22% off the average retail price of $100.14.
tube of creamTube of cream
DosageQuantityPrice as low asPrice per unit
30g of 100000 units/g1 tube$14.17$14.17
15g of 100000 units/g1 tube$8.12$8.12

Typical dosage for Nystatin topical

  • Cream and ointment: Apply a generous amount to the affected area(s) 2 times a day until the infection is healed or as directed by your prescriber.
  • Powder: Apply to the affected area(s) 2 to 3 times daily until the infection is healed or as directed by your prescriber
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How much does Nystatin topical cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
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What are alternatives to Nystatin topical?

There are a number of medications that your doctor can prescribe in place of Nystatin topical. Compare a few possible alternatives below.
Nystatin topical
$7.73Lowest GoodRx priceView prices
Used for:
$13.01Lowest GoodRx priceView prices
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Nystatin topical images

yellow - Nystatin 100,000unit/mL Suspension
This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000unit/mL Suspension
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This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000unit/mL Suspension
yellow - Nystatin 100,000unit/ml Suspension
This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000unit/ml Suspension
yellow - Nystatin 100,000unit/ml Suspension
This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000unit/ml Suspension
yellow - Nystatin 100,000units/mL Suspension
This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000units/mL Suspension
yellow - Nystatin 100,000units/mL Suspension
This medicine is Yellow Oral Suspension.yellow - Nystatin 100,000units/mL Suspension

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References

Best studies we found

Muddasani, S., et al. (2023). The Persistence of Nystatin Use for Dermatophyte Infections. The Journal of Drugs in Dermatology.

Northstar Rx LLC. (2025). NYSTATIN powder. DailyMed.

Padagis Israel Pharmaceuticals Ltd. (2025). NYSTATIN ointment. DailyMed.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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